Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	91547
Country	India

Category	Oncology
Manuscript Type	Letter to the Editor
Article Title	Hemostatic radiotherapy for bleeding gastrointestinal tumors
Manuscript Source	Unsolicited Manuscript
All Author List	Vrushab Rao, Soumya Singh and Bhooshan Zade
Funding Agency and Grant Number
Corresponding Author	Vrushab Rao, MBBS, Doctor, Department of Cyberknife Radiosurgery and Radiation Oncology, Ruby Hall Clinic, 40 Sassoon Road, Pune 411001, Maharashtra, India. raovrushab@gmail.com
Key Words	Gastrointestinal tumors; Hemostatic radiotherapy; Palliative radiotherapy; Acute bleeding; Hypofractionation
Core Tip	Hemostatic radiotherapy (RT), a non-invasive approach, is used in bleeding gastrointestinal (GI) tumors to induce tumor shrinkage and diminish blood supply. This therapy reduces tumor size, seals ruptured blood vessels and reduces bleeding. It also fosters fibrotic tissue formation and enhances platelet adhesion to the vascular endothelium. Hemostatic RT is particularly relevant when traditional interventions are insufficient or contraindicated, and can prevent recurrent bleeding in patients with a history of GI bleeding tumors. The optimal dose fractionation for hemostatic RT is debated, but hypofractionation schedules have proven effective for tumor control and patient compliance.
Citation	Rao V, Singh S, Zade B. Hemostatic radiotherapy for bleeding gastrointestinal tumors. World J Gastrointest Oncol 2024; 16(5): 2261-2263

Received	2023-12-30 11:07
Peer-Review Started	2023-12-30 11:07
To Make the First Decision
Return for Revision	2024-02-18 02:15
Revised	2024-02-20 03:02
Second Decision	2024-03-27 02:36
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-03-27 04:46
Articles in Press	2024-03-27 04:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-04-22 00:40

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: Https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com