Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	32970
Country	Argentina

Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Rectification of oxygen transfer through the rat colonic epithelium
Manuscript Source	Invited Manuscript
All Author List	Fernando D Saraví, Graciela E Carra, Daniel A Matus and Jorge E Ibáñez
Funding Agency and Grant Number	Funding Agency Grant Number The Secretaría de Ciencia, Técnica y Posgrado, National University of Cuyo, Mendoza 5500 Argentina to Saraví FD 06/J457
Corresponding Author	Fernando D Saraví, MD, PhD, Full Professor, Institute of Physiology, Faculty of Medical Sciences, National University of Cuyo, Parque General San Martín s/n, Mendoza 5500, Argentina. fernando.saravi@hotmail.es
Key Words	Colonic epithelium; Hypoxia; Oxygen diffusion; Short-circuit current; Ussing chamber
Core Tip	The physiological dependence of the colonic epithelium on oxygen provided from the serosal side is not only due to the structure of its blood supply and the low oxygen pressure of colonic intraluminal contents, since it is also observed in isolated mucosa preparations. This study demonstrates for the first time that a much larger partial pressure difference is needed for oxygen transfer from the mucosal side to the serosal side of the epithelium than for transfer in the opposite direction, a phenomenon that may be considered a rectifying behavior.
Citation	Saraví FD, Carra GE, Matus DA, Ibáñez JE. Rectification of oxygen transfer through the rat colonic epithelium. World J Gastrointest Pathophysiol 2017; 8(2): 59-66

Received	2017-02-01 12:38
Peer-Review Started	2017-02-08 16:13
To Make the First Decision	2017-03-08 09:36
Return for Revision	2017-03-09 16:11
Revised	2017-03-24 06:34
Second Decision	2017-04-18 15:11
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2017-04-24 10:45
Articles in Press	2017-04-24 10:45
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-05-13 18:09

ISSN	2150-5330 (online)
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