Publication Name	World Journal of Dermatology
Manuscript ID	33543
Country	United Kingdom

Category	Dermatology
Manuscript Type	Minireviews
Article Title	Atopic eczema treatment now and in the future: Targeting the skin barrier and key immune mechanisms in human skin
Manuscript Source	Unsolicited Manuscript
All Author List	David C Bell and Sara J Brown
Funding Agency and Grant Number
Corresponding Author	Sara J Brown, Professor of Molecular and Genetic Dermatology, Wellcome Trust Senior Research Fellow in Clinical Science, Honorary Consultant Dermatologist, Skin Research Group, School of Medicine, Ninewells Hospital and Medical School, University of Dundee, James Arrott Drive, Dundee DD1 9SY, Scotland, United Kingdom. s.j.brown@dundee.ac.uk
Key Words	Atopic eczema; Novel treatment; Filaggrin; Skin barrier; Immune dysfunction
Core Tip	Atopic eczema (atopic dermatitis) is an itchy inflammatory skin disease with complex aetiology, including impairment in barrier function and concomitant inflammation. Increased understanding of the molecular mechanisms in eczema pathogenesis has opened up opportunities for new therapeutic targets. This review summaries current understanding and highlights some novel treatments in development.
Citation	Bell DC, Brown SJ. Atopic eczema treatment now and in the future: Targeting the skin barrier and key immune mechanisms in human skin. World J Dermatol 2017; 6(3): 42-51

Received	2017-02-15 08:55
Peer-Review Started	2017-02-15 19:07
To Make the First Decision	2017-03-06 17:49
Return for Revision	2017-03-07 14:23
Revised	2017-03-14 05:57
Second Decision	2017-03-24 11:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2017-04-07 15:32
Articles in Press	2017-04-07 15:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-07-18 08:35

ISSN	2218-6190 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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