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9/28/2016 3:07:00 PM | Browse: 461 | Download: 955
Publication Name World Journal of Clinical Infectious Diseases
Manuscript ID 25846
Country/Territory United States
Received
2016-03-24 08:44
Peer-Review Started
2016-03-24 16:33
To Make the First Decision
2016-04-15 08:54
Return for Revision
2016-04-15 11:56
Revised
2016-04-28 02:41
Second Decision
2016-05-16 08:45
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-06-02 16:04
Articles in Press
2016-06-02 16:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-08-18 19:52
Publish the Manuscript Online
2016-08-25 09:10
ISSN 2220-3176 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Challenges in management of recurrent and refractory Clostridium difficile infection
Manuscript Source Invited Manuscript
All Author List Anne M Meehan, Raseen Tariq and Sahil Khanna
Funding Agency and Grant Number
Corresponding Author Sahil Khanna, MBBS, MS, Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, United States. khanna.sahil@mayo.edu
Key Words Clostridium difficile infection; Epidemiology; Outcomes; Treatment; Fecal microbiota transplantation
Core Tip Recurrent Clostridium difficile infection (RCDI) is common and can be difficult to treat. Clostridia spores transmit disease. They are ubiquitous and hard to eradicate. The composition of the gut microbiome plays an essential yet poorly understood role in main-taining overall health, and in protecting against Clostri-dium difficile (C. difficile) infection. Antibiotic induced dysbiosis of the microbiome is a key contributor to RCDI. Here we review how C. difficile spores and altera-tions in the microbiome contribute to RCDI.
Publish Date 2016-08-25 09:10
Citation Meehan AM, Tariq R, Khanna S. Challenges in management of recurrent and refractory Clostridium difficile infection. World J Clin Infect Dis 2016; 6(3): 28-36
URL http://www.wjgnet.com/2220-3176/full/v6/i3/28.htm
DOI http://dx.doi.org/10.5495/wjcid.v6.i3.28
Full Article (PDF) WJCID-6-28.pdf
Full Article (Word) WJCID-6-28.doc
Manuscript File 25846-Review.docx
Answering Reviewers 25846-Answering reviewers.pdf
Audio Core Tip 25846-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 25846-Conflict-of-interest statement.pdf
Copyright License Agreement 25846-Copyright assignment.pdf
Peer-review Report 25846-Peer-review(s).pdf
Scientific Misconduct Check 25846-Scientific misconduct check.pdf
Scientific Editor Work List 25846-Scientific editor work list.pdf