BPG is committed to discovery and dissemination of knowledge
Featured Articles
11/9/2016 2:28:00 PM | Browse: 837 | Download: 1136
 |
Received |
|
2016-04-22 14:39 |
|
Peer-Review Started |
|
2016-04-23 08:02 |
|
To Make the First Decision |
|
2016-06-06 10:37 |
|
Return for Revision |
|
2016-06-06 15:46 |
|
Revised |
|
2016-06-24 22:48 |
|
Second Decision |
|
2016-08-11 10:50 |
|
Accepted by Journal Editor-in-Chief |
|
2016-08-12 09:15 |
|
Accepted by Company Editor-in-Chief |
|
2016-08-18 11:24 |
|
Articles in Press |
|
2016-08-18 11:24 |
 |
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2016-10-31 15:17 |
|
Publish the Manuscript Online |
|
2016-11-08 20:12 |
| ISSN |
2220-3249 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Virology |
| Manuscript Type |
Basic Study |
| Article Title |
Antiretroviral naive and treated patients: Discrepancies of B cell subsets during the natural course of human immunodeficiency virus type 1 infection
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Olga Tsachouridou, Lemonia Skoura, Pantelis Zebekakis, Apostolia Margariti, Adamantini Georgiou, Dimitrios Bougiouklis, Dimitrios Pilalas, Antonios Galanos, Michael Daniilidis and Symeon Metallidis |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Olga Tsachouridou, MD, PhD, Research Associate of Infectious Diseases Unit, 1st Internal Medicine Department, Infectious Diseases Division, Medical School, Aristotle University of Thessaloniki, 1 Stilponos Kyriakidi Street, 54636 Thessaloniki, Greece. olgat_med@hotmail.com
|
| Key Words |
B cell subpopulations; Time-trend; Memory cells; Human immunodeficiency virus infection; Highly active antiretroviral therapy |
| Core Tip |
During the progress of human immunodefi-ciency virus (HIV) infection and viral replication functional irritations of memory B-cell (BMC) compart-ment occur. Depletion of BMCs is one hallmark of deregulation in HIV-1 infection. Diminished levels of IgM+ BMCs are also noted. Additionally, resting BMCs are severely impaired and defective B-cell subsets, like exhausted and activated BMCs circulate in peripheral blood. Significant fluctuations of these B cells’ frequencies are recorded over time and antiretroviral therapy may play a role on this observation. Assessing these populations could potentially lead to improvement in assessing vaccine responses and tracing vulnerable patients to certain infections.
|
| Publish Date |
2016-11-08 20:12 |
| Citation |
Tsachouridou O, Skoura L, Zebekakis P, Margariti A, Georgiou A, Bougiouklis D, Pilalas D, Galanos A, Daniilidis M, Metallidis S. Antiretroviral naive and treated patients: Discrepancies of B cell subsets during the natural course of human immunodeficiency virus type 1 infection. World J Virol 2016; 5(4): 155-160 |
| URL |
http://www.wjgnet.com/2220-3249/full/v5/i4/155.htm |
| DOI |
http://dx.doi.org/10.5501/wjv.v5.i4.155 |
© 2004-2024 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
