Publication Name	World Journal of Stem Cells
Manuscript ID	28481
Country	Canada

Received	2016-07-01 17:09
Peer-Review Started	2016-07-03 16:17
To Make the First Decision	2016-09-05 09:09
Return for Revision	2016-09-18 11:54
Revised	2016-09-20 00:19
Second Decision	2016-10-10 09:35
Accepted by Journal Editor-in-Chief	2016-10-10 16:32
Accepted by Company Editor-in-Chief	2016-10-24 14:44
Articles in Press	2016-10-24 14:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-01-06 13:49
Publish the Manuscript Online	2017-01-18 15:19

ISSN	1948-0210 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Website	http://www.wjgnet.com

Category	Cell Biology
Manuscript Type	Review
Article Title	Optimizing stem cells for cardiac repair: Current status and new frontiers in regenerative cardiology
Manuscript Source	Invited Manuscript
All Author List	Shant Der Sarkissian, Thierry Lévesque and Nicolas Noiseux
Funding Agency and Grant Number
Corresponding Author	Nicolas Noiseux, MD, FRCS(C), MSc (Molecular Biology), BSc (Biochemistry), Cardiac Surgeon, Full Professor of Surgery, Director of Research Cardiac Surgery, Department of Surgery, Faculté de Médecine, Université de Montréal, Pavillon Hôtel-Dieu 3840, Saint-Urbain St., Local 2-420, Montreal, QC H3C 3J7, Canada. noiseuxn@videotron.ca
Key Words	Stem cell; Regenerative medicine; Cellular cardiomyoplasty; Preconditioning; Myocardial infarction; Heart failure; Viability; Paracrine activity; Transplan­tation; Pharmaco-optimizer
Core Tip	Cell therapy has the potential to improve healing of the ischemic heart, to repopulate injured myocardium and restore cardiac function in ischemic and non-ischemic cardiomyopathy. However, one of the biggest impediments lessening clinical effectiveness of cell therapy is the poor viability, retention and functionality of transplanted cells. This review looks as various stem cell ex vivo preconditioning and reprogram-ming methods aimed at enhancing the therapeutic potential of stem cells for heart failure treatment.
Publish Date	2017-01-18 15:19
Citation	Der Sarkissian S, Lévesque T, Noiseux N. Optimizing stem cells for cardiac repair: Current status and new frontiers in regenerative cardiology. World J Stem Cells 2017; 9(1): 9-25
URL	http://www.wjgnet.com/1948-0210/full/v9/i1/9.htm
DOI	http://dx.doi.org/10.4252/wjsc.v9.i1.9

Full Article (PDF)	WJSC-9-9.pdf
Full Article (Word)	WJSC-9-9.doc
Manuscript File	28481-Review.docx
Answering Reviewers	28481-Answering reviewers.pdf
Audio Core Tip	28481-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	28481-Conflict-of-interest statement.pdf
Copyright License Agreement	28481-Copyright assignment.pdf
Peer-review Report	28481-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	28481-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	28481-Scientific misconduct check.pdf
Scientific Editor Work List	28481-Scientific editor work list.pdf