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2/17/2017 5:30:00 PM | Browse: 818 | Download: 1497
Publication Name World Journal of Experimental Medicine
Manuscript ID 29787
Country/Territory United States
Received
2016-08-27 20:58
Peer-Review Started
2016-08-29 19:33
To Make the First Decision
2016-11-11 09:29
Return for Revision
2016-11-14 17:02
Revised
2016-11-19 02:11
Second Decision
2016-11-29 09:54
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-12-09 17:33
Articles in Press
2016-12-09 17:33
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-02-09 15:06
Publish the Manuscript Online
2017-02-17 10:11
ISSN 2220-315x (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Research & Experimental Medicine
Manuscript Type Review
Article Title Effect of aging on stem cells
Manuscript Source Invited Manuscript
All Author List Abu Shufian Ishtiaq Ahmed, Matilda HC Sheng, Samiksha Wasnik, David J Baylink and Kin-Hing William Lau
Funding Agency and Grant Number
Funding Agency Grant Number
None
Corresponding Author Kin-Hing William Lau, PhD, Musculoskeletal Disease Center, Jerry L. Pettis Memorial VA Medical Center, 11201 Benton Street, Loma Linda, CA 92357, United States. william.lau@med.va.gov
Key Words Aging; Biological aging; Cellular aging; Adult stem cells; Premature aging; Mesenchymal stem cell; Stem cell renewal; Tissue regeneration
Core Tip Stem cells have the remarkable self-renewal capability and the amazing ability to differentiate into all cell types. It is generally believe that stem cells are the main source that provides cells to repair and re?generate damaged tissues and organs. However, there is now compelling evidence that the aging process has a deleterious effect on stem cells, and that the aging effects on stem cells may have play essential roles in the pathophysiology of the various aging-associated diseases. This review discusses briefly the relationship of aging-associated stem cell dysfunction and the various aging-associated ailments, and several proposed concepts on the molecular mechanism of aging-related stem cell dysfunction.
Publish Date 2017-02-17 10:11
Citation Ahmed ASI, Sheng MHC, Wasnik S, Baylink DJ, Lau KHW. Effect of aging on stem cells. World J Exp Med 2017; 7(1): 1-10
URL http://www.wjgnet.com/2220-315X/full/v7/i1/1.htm
DOI http://dx.doi.org/10.5493/wjem.v7.i1.1
Full Article (PDF) WJEM-7-1.pdf
Full Article (Word) WJEM-7-1.doc
Manuscript File 29787-Review.doc
Answering Reviewers 29787-Answering reviewers.pdf
Audio Core Tip 29787-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 29787-Conflict-of-interest statement.pdf
Copyright License Agreement 29787-Copyright assignment.pdf
Peer-review Report 29787-Peer-review(s).pdf
Scientific Misconduct Check 29787-Scientific misconduct check.pdf
Scientific Editor Work List 29787-Scientific editor work list.pdf