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3/29/2017 3:33:00 PM | Browse: 726 | Download: 2020
Publication Name World Journal of Methodology
Manuscript ID 31444
Country/Territory India
Received
2016-11-18 10:31
Peer-Review Started
2016-11-22 10:01
To Make the First Decision
2017-01-14 12:01
Return for Revision
2017-01-16 21:00
Revised
2017-01-21 21:43
Second Decision
2017-02-23 18:28
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-03-13 12:14
Articles in Press
2017-03-13 12:14
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-03-20 09:11
Publish the Manuscript Online
2017-03-24 10:35
ISSN 2222-0682 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Dermatology
Manuscript Type Observational Study
Article Title Patch testing and cross sensitivity study of adverse cutaneous drug reactions due to anticonvulsants: A preliminary report
Manuscript Source Invited Manuscript
All Author List TN Shiny, Vikram K Mahajan, Karaninder S Mehta, Pushpinder S Chauhan, Ritu Rawat and Rajni Sharma
Funding Agency and Grant Number
Corresponding Author Dr. Vikram K Mahajan, MBBS, MD, Department of Dermatology, Venereology and Leprosy, Dr. R. P. Govt. Medical College, Tanda Hospital Rd, Kangra, Himachal Pradesh 176001, India. vkm1@rediffmail.com
Key Words Anticonvulsant hypersensitivity syndrome; Carbamazepine; Sodium valproate; Drug rash with eosinophilia with or without systemic involvement; Drug patch test; Lamotrigine; Phenobarbitone; Phenytoin; Stevens-Johnsons syndrome; Toxic epidermal necrolysis
Core Tip Anticonvulsants account for 20% of all adverse cutaneous drug reactions (ACDRs) while cross-reactions occur frequently among carbamazepine, phenytoin, phenobarbitone necessitating careful prescriptions. The clinical presentation alone is not diagnostic and identification of offending drug needs causality assessment that may be misleading in patients on multiple medications. Drug provocation, skin prick or intradermal tests have ethical issues for possibility of precipitating more severe reactions. Basophil degranulation/lymphocyte activation or drug specific IgE radioallergosorbent tests, histamine release and passive haemagglutination tests have limited use in clinical practice. Drug patch testing appears useful in anticonvulsant ACDRs, drug imputability and cross-reactions established clinically.
Publish Date 2017-03-24 10:35
Citation Shiny TN, Mahajan VK, Mehta KS, Chauhan PS, Rawat R, Sharma R. Patch testing and cross sensitivity study of adverse cutaneous drug reactions due to anticonvulsants: A preliminary report. World J Methodol 2017; 7(1): 25-32
URL http://www.wjgnet.com/2222-0682/full/v7/i1/25.htm
DOI http://dx.doi.org/10.5662/wjm.v7.i1.25
Full Article (PDF) WJM-7-25.pdf
Full Article (Word) WJM-7-25.doc
Manuscript File 31444-Review.doc
Answering Reviewers 31444-Answering reviewers.pdf
Audio Core Tip 31444-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 31444-Conflict-of-interest statement.pdf
Copyright License Agreement 31444-Copyright assignment.pdf
Institutional Review Board Approval Form or Document 31444-Institutional review board statement.pdf
Peer-review Report 31444-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 31444-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 31444-Scientific misconduct check.pdf
Scientific Editor Work List 31444-Scientific editor work list.pdf