Publication Name	World Journal of Immunology
Manuscript ID	10482
Country	United States

Received	2014-04-02 11:24
Peer-Review Started	2014-04-02 16:35
To Make the First Decision	2014-04-15 15:16
Return for Revision	2014-05-21 10:07
Revised	2014-05-22 03:42
Second Decision	2014-06-20 12:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-06-20 12:14
Articles in Press	2014-06-20 12:14
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-07-15 14:59
Publish the Manuscript Online	2014-07-27 18:55

ISSN	2219-2824 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Immunology
Manuscript Type	Review
Article Title	Gut immune response in the presence of hepatitis C virus infection
Manuscript Source	Invited Manuscript
All Author List	Helal F Hetta, Minesh J Mehta and Mohamed Tarek M Shata
Funding Agency and Grant Number	Funding Agency Grant Number Egyptian Government Scholarship for Helal Hetta Merck Investigator Initiated Studies (IIS) IISP 40458 (to Shata)
Corresponding Author	Mohamed Tarek M Shata, MD, PhD, Department of Internal Medicine, Division of Digestive Diseases, University of Cincinnati, 231 Albert B. Sabin Way, Cincinnati, OH 45267, United States. mohamed.shata@uc.edu
Key Words	Hepatitis C virus; Colonic Treg; Mucosal; Immune regulation; Liver inflammation; IL-28B
Core Tip	Chronic Hepatitis C (CHC) is a global worldwide health problem with approximately 200 million people worldwide infected with hepatitis C virus (HCV). It is also a major cause of chronic liver infection that often leads to chronic hepatitis which may progress to cirrhosis, fibrosis and finally hepatocellular carcinoma. In CHC, immune responses play an important role in HCV pathogenesis and responses to therapy. Intra-hepatic immune responses to HCV are highly regulated. There is a clear relationship between hepatic immune responses and mucosal immune response in the gut. Additionally, genetic immunological markers have been proposed to predict response to HCV treatment, and outcome of infection.
Publish Date	2014-07-27 18:55
Citation	Hetta HF, Mehta MJ, Shata MTM. Gut immune response in the presence of hepatitis C virus infection. World J Immunol 2014; 4(2): 52-62
URL	http://www.wjgnet.com/2219-2824/full/v4/i2/52.htm
DOI	http://dx.doi.org/10.5411/wji.v4.i2.52

Full Article (PDF)	WJI-4-52.pdf
Full Article (Word)	WJI-4-52.doc
Manuscript File	10482-Review.docx
Answering Reviewers	10482-Answering reviewers.pdf
Copyright License Agreement	10482-Copyright assignment.pdf
Peer-review Report	10482-Peer review(s).pdf
Scientific Misconduct Check	10482-CrossCheck.jpg
Scientific Editor Work List	10482-Scientific editor work list.pdf