Publication Name	World Journal of Hepatology
Manuscript ID	13705
Country	Italy

Received	2014-08-29 08:37
Peer-Review Started	2014-08-29 17:56
To Make the First Decision	2014-10-14 18:05
Return for Revision	2014-10-20 16:52
Revised	2014-11-11 13:16
Second Decision	2015-01-04 15:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-01-12 14:33
Articles in Press	2015-01-12 14:33
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-03-29 15:47
Publish the Manuscript Online	2015-04-14 18:13

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Medicine, Research & Experimental
Manuscript Type	Topic Highlights
Article Title	Cirrhosis and portal hypertension: The importance of risk stratification, the role of hepatic venous pressure gradient measurement
Manuscript Source	Invited Manuscript
All Author List	Vincenzo La Mura, Antonio Nicolini, Giulia Tosetti and Massimo Primignani
Funding Agency and Grant Number
Corresponding Author	Vincenzo La Mura, MD, PhD, Fondazione IRCCS, Ca’ Granda, Ospedale Maggiore Policlinico, via F. Sforza, 20100 Milano, Italy. vin.lamura@gmail.com
Key Words	Cirrhosis; Portal hypertension; Hepatic venous pressure gradient; Variceal bleeding; Prognosis
Core Tip	Recently a pathophysiological classification of cirrhosis has been strongly encouraged. Hepatic venous pressure gradient (HVPG) measurement is the most reliable tool to estimate the severity of portal hypertension in cirrhosis but several methodological concerns have limited its use in clinical practice. The article summarizes the results published about the prognostic value of HVPG and originally offers a critical revision of the information provided by this hemodynamic parameter on top of the most widely used models based on non-hemodynamic parameters.
Publish Date	2015-04-14 18:13
Citation	La Mura V, Nicolini A, Tosetti G, Primignani M. Cirrhosis and portal hypertension: The importance of risk stratification, the role of hepatic venous pressure gradient measurement. World J Hepatol 2015; 7(4): 688-695
URL	http://www.wjgnet.com/1948-5182/full/v7/i4/688.htm
DOI	http://dx.doi.org/10.4254/wjh.v7.i4.688

Full Article (PDF)	WJH-7-688.pdf
Full Article (Word)	WJH-7-688.doc
Manuscript File	13705-Review.doc
Answering Reviewers	13705-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	13705-Conflict-of-interest statement.pdf
Copyright License Agreement	13705-Copyright assignment.pdf
Peer-review Report	13705-Peer review(s).pdf
Scientific Misconduct Check	13705-CrossCheck.jpg
Scientific Editor Work List	13705-Scientific editor work list.pdf