| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
|
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Prospective Study |
| Article Title |
Serum proinflammatory cytokines and nutritional status in pediatric chronic liver disease
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Daniele Santetti, Maria Inês de Albuquerque Wilasco, Cristina Toscani Leal Dornelles, Isabel Cristina Ribas Werlang, Fernanda Urruth Fontella, Carlos Oscar Kieling, Jorge Luiz dos Santos, Sandra Maria Gonçalves Vieira and Helena Ayako Sueno Goldani |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Fundo de Incentivo a Pesquisa, Hospital de Clinicas de Porto Alegre |
|
| Post-Graduate Program of Child and Adolescent Health-UFRGS |
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| Conselho Nacional de Desenvolvimento Cientifico e Tecnológico (CNPq), Brazil |
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| Corresponding Author |
Daniele Santetti, MSc, Post-Graduate Program of Child and Adolescent Health, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rua Ramiro Barcelos, 2350 Porto Alegre, Rio Grande do Sul 90035-903, Brazil. danisantetti@gmail.com |
| Key Words |
Cytokines; Interleukin-6; Malnutrition; Cirrhosis; Child |
| Core Tip |
Inflammatory activity has been suggested as a component of the pathogenesis of illness-related malnutrition. Several studies have evaluated proinflammatory cytokines in pediatric chronic liver disease, but none have addressed the possible association between these biomarkers and nutritional status. This study showed that the interleukin-6 levels were significantly increased in children and adolescents at nutritional risk. To the best of our knowledge, this is the first study to analyze the relationship between the cytokine levels and nutritional status in children and adolescents with chronic liver disease. |
| Publish Date |
2015-08-08 15:26 |
| Citation |
Santetti D, de Albuquerque Wilasco MI, Dornelles CTL, Werlang ICR, Fontella FU, Kieling CO, dos Santos JL, Vieira SMG, Goldani HAS. Serum proinflammatory cytokines and nutritional status in pediatric chronic liver disease. World J Gastroenterol 2015; 21(29): 8927-8934 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i29/8927.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i29.8927 |
