| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Association between hepatocellular carcinoma and tumor necrosis factor alpha polymorphisms in South Korea
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Suk Pyo Shin, Nam Keun Kim, Ju Hwan Kim, Ju Ho Lee, Jung Oh Kim, Sung Hwan Cho, Hana Park, Mi Na Kim, Kyu Sung Rim and Seong Gyu Hwang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Basic Science Research Program through National Research Foundation of Korea Grants |
NRF-2012R1A1A2007033 |
| Basic Science Research Program through National Research Foundation of Korea Grants |
2009-0093821 |
|
| Corresponding Author |
Seong Gyu Hwang, MD, PhD, Professor, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Yatapro 59, Bundang-gu, Seongnam 463-712, South Korea. sghwang@cha.ac.kr |
| Key Words |
Tumor necrosis factor-alpha; Polymorphism; Single nucleotide; Carcinoma; Hepatocellular |
| Core Tip |
We genotyped five single nucleotide polymorphisms [Tumor necrosis factor alpha (TNF-α) -1031T>C, -863C>A, -857C>T, -308G>A, and -238G>A] in hepatocellular carcinoma (HCC) patients and control subjects. A number of genotype combinations and some haplotypes had association with HCC. In addition, HCC Okuda stage Ⅲ cases with the TNF-α -1031 TT genotype had a better prognosis than those with the CC genotype. |
| Publish Date |
2015-12-09 17:57 |
| Citation |
Shin SP, Kim NK, Kim JH, Lee JH, Kim JO, Cho SH, Park H, Kim MN, Rim KS, Hwang SG. Association between hepatocellular carcinoma and tumor necrosis factor alpha polymorphisms in South Korea. World J Gastroenterol 2015; 21(46): 13064-13072 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i46/13064.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i46.13064 |
