Publication Name	World Journal of Hepatology
Manuscript ID	25498
Country	Russia

Received	2016-03-12 16:24
Peer-Review Started	2016-03-13 17:20
To Make the First Decision	2016-04-18 19:37
Return for Revision	2016-04-20 15:11
Revised	2016-04-25 16:42
Second Decision	2016-05-09 18:21
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2016-05-27 11:27
Articles in Press	2016-05-27 11:27
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-05-30 15:22
Publish the Manuscript Online	2016-06-02 15:41

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Mechanisms of adaptation of the hepatic vasculature to the deteriorating conditions of blood circulation in liver cirrhosis
Manuscript Source	Invited Manuscript
All Author List	Dmitry Victorovich Garbuzenko, Nikolay Olegovich Arefyev and Dmitry Vladimirovich Belov
Funding Agency and Grant Number
Corresponding Author	Dmitry Victorovich Garbuzenko, MD, PhD, Professor, Department of Faculty Surgery, South Ural State Medical University, Box 12317, 454092 Chelyabinsk, Russia. garb@inbox.ru
Key Words	Liver cirrhosis; Endothelial dysfunction; Sinusoidal remodeling; Intrahepatic angiogenesis; Pathogenesis of portal hypertension
Core Tip	Besides gross hepatic structural disorders related to diffuse fibrosis and formation of regenerative nodules, the complex morphofunctional rearrangement of the hepatic microvascular bed and intrahepatic angiogenesis play important roles in hemodynamic disturbances in liver cirrhosis. In spite of the fact that these changes of the hepatic vasculature are the compen-satory-adaptive reaction to the deteriorating conditions of blood circulation, they contribute to the progression of disease and development of serious complications, in particular, related to portal hypertension.
Publish Date	2016-06-02 15:41
Citation	Garbuzenko DV, Arefyev NO, Belov DV. Mechanisms of adaptation of the hepatic vasculature to the deteriorating con­ditions of blood circulation in liver cirrhosis. World J Hepatol 2016; 8(16): 665-672
URL	http://www.wjgnet.com/1948-5182/full/v8/i16/665.htm
DOI	http://dx.doi.org/10.4254/wjh.v8.i16.665

Full Article (PDF)	WJH-8-665.pdf
Full Article (Word)	WJH-8-665.doc
Manuscript File	25498-Review.doc
Answering Reviewers	25498-Answering reviewers.pdf
Audio Core Tip	25498-Audio core tip.MP3
Conflict-of-Interest Disclosure Form	25498-Conflict-of-interest statement.pdf
Copyright License Agreement	25498-Copyright assignment.pdf
Peer-review Report	25498-Peer-review(s).pdf
Scientific Misconduct Check	25498-Scientific misconduct check.pdf
Scientific Editor Work List	25498-Scientific editor work list.pdf