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7/4/2016 2:42:00 PM | Browse: 1203 | Download: 1857
Publication Name World Journal of Gastroenterology
Manuscript ID 26352
Country China
Received
2016-04-06 09:01
Peer-Review Started
2016-04-06 09:51
To Make the First Decision
2016-05-12 10:24
Return for Revision
2016-05-12 15:29
Revised
2016-05-13 13:26
Second Decision
2016-06-01 18:55
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-06-02 15:35
Articles in Press
2016-06-02 15:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
2016-06-20 18:18
Typeset the Manuscript
2016-06-23 12:17
Publish the Manuscript Online
2016-07-04 14:42
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Allergy
Manuscript Type Observational Study
Article Title Low expression of ARID1A correlates with poor prognosis in intrahepatic cholangiocarcinoma
Manuscript Source Unsolicited Manuscript
All Author List Song-Zhu Yang, An-Qiang Wang, Juan Du, Jian-Tao Wang, Wei-Wei Yu, Qing Liu, Yan-Fang Wu and Shu-Guang Chen
Funding Agency and Grant Number
Corresponding Author Shu-Guang Chen, MD, Professor, Department of Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 1 Shuaifuyuan, Wangfujing, Dongcheng District, Beijing 100730, China. pumchcsg@163.com
Key Words ARID1A; Intrahepatic cholangiocarcinoma; Progression; Prognosis; Biomarker
Core Tip We investigated the relationship between ARID1A expression and clinicopathologic parameters, as well as its prognostic value, for patients with intrahepatic cholangiocarcinoma (IHCC). We examined ARID1A protein and mRNA expression in IHCC and paracarcinomatous (PC) tissue from 57 patients with IHCC. The mean ARID1A protein and mRNA expression levels in IHCC tissues were significantly lower than those in PC tissues and normal liver tissues. Low ARID1A expression was significantly associated with tumor nodules, vein invasion, and recurrence. Low ARID1A expression was significantly associated with worse overall survival in multivariate analyses. ARID1A may be a potential prognostic biomarker candidate in IHCC.
Publish Date 2016-07-04 14:42
Citation Yang SZ, Wang AQ, Du J, Wang JT, Yu WW, Liu Q, Wu YF, Chen SG. Low expression of ARID1A correlates with poor prognosis in intrahepatic cholangiocarcinoma. World J Gastroenterol 2016; 22(25): 5814-5821
URL http://www.wjgnet.com/1007-9327/full/v22/i25/5814.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i25.5814
Full Article (PDF) WJG-22-5814.pdf
Full Article (Word) WJG-22-5814.doc
Manuscript File 26352-Review.docx
Answering Reviewers 26352-Answering reviewers.pdf
Audio Core Tip 26352-Audio core tip.mp3
Biostatistics Review Certificate 26352-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 26352-Conflict-of-interest statement.pdf
Copyright License Agreement 26352-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) 26352-Conflict-of-interest statement.pdf
Institutional Review Board Approval Form or Document 26352-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 26352-Language certificate.pdf
Peer-review Report 26352-Peer-review(s).pdf
Scientific Misconduct Check 26352-Scientific misconduct check.pdf
Scientific Editor Work List 26352-Scientific editor work list.pdf