Publication Name	World Journal of Gastroenterology
Manuscript ID	26879
Country	Spain

Received	2016-04-29 15:00
Peer-Review Started	2016-05-01 17:20
To Make the First Decision	2016-06-20 14:04
Return for Revision	2016-06-20 17:20
Revised	2016-07-04 22:38
Second Decision	2016-07-25 08:08
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2016-08-05 17:52
Articles in Press	2016-08-05 17:52
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-09-01 18:23
Publish the Manuscript Online	2016-09-08 10:53

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Transplantation
Manuscript Type	Review
Article Title	Tolerance in liver transplantation: Biomarkers and clinical relevance
Manuscript Source	Invited Manuscript
All Author List	Alberto Baroja-Mazo, Beatriz Revilla-Nuin, Pascual Parrilla, Laura Martínez-Alarcón, Pablo Ramírez and José Antonio Pons
Funding Agency and Grant Number	Funding Agency Grant Number Fondo de Investigaciones Sanitarias Grants PI12/02042
Corresponding Author	José Antonio Pons, MD, PhD, Division of Gastroenterology and Hepatology and Liver Transplant Unit, University Hospital Virgen de la Arrixaca, Ctra. Madrid-Cartagena, s/n, 30120 Murcia, Spain. joseapons.imib.arrixaca@gmail.com
Key Words	Liver transplantation; Operational tolerance; Regulatory T cells; Dendritic cells; Biomarkers
Core Tip	Nowadays, the major goal in transplantation is to understand and induce tolerance. Although a plethora of genetic and cellular biomarkers is raising and being validated worldwide in large multi-center clinical trials, little is known about the impact of immunosuppression withdrawal on pre-existing complications derived from the long-term administration of immunosuppressive drugs and the side effects associated with them. The future of liver transplantation is aimed to develop new therapies which increase the actual low tolerant vs non-tolerant recipients ratio.
Publish Date	2016-09-08 10:53
Citation	Baroja-Mazo A, Revilla-Nuin B, Parrilla P, Martínez-Alarcón L, Ramírez P, Pons JA. Tolerance in liver transplantation: Biomarkers and clinical relevance. World J Gastroenterol 2016; 22(34): 7676-7691
URL	http://www.wjgnet.com/1007-9327/full/v22/i34/7676.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i34.7676

Full Article (PDF)	WJG-22-7676.pdf
Full Article (Word)	WJG-22-7676.doc
Manuscript File	26879-Review.docx
Answering Reviewers	26879-Answering reviewers.pdf
Audio Core Tip	26879-Audio core tip.mp4
Conflict-of-Interest Disclosure Form	26879-Conflict-of-interest statement.pdf
Copyright License Agreement	26879-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	26879-Grant application form(s).pdf
Peer-review Report	26879-Peer-review(s).pdf
Scientific Misconduct Check	26879-Scientific misconduct check.pdf
Scientific Editor Work List	26879-Scientific editor work list.pdf