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9/3/2014 5:13:00 PM | Browse: 704 | Download: 550
Publication Name World Journal of Gastroenterology
Manuscript ID 3042
Country China
Received
2013-04-07 10:31
Peer-Review Started
2013-04-17 12:19
To Make the First Decision
2013-06-09 10:14
Return for Revision
2013-06-13 15:40
Revised
Second Decision
2013-09-05 11:18
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-09-05 12:47
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-01-08 19:51
Publish the Manuscript Online
2014-01-26 20:08
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research & Experimental
Manuscript Type Autobiography
Article Title Portal inflow preservation during portal diversion in small-for-size syndrome
Manuscript Source Invited Manuscript
All Author List Xian-Qiang Wang, Yue-Fang Xu, Jing-Wang Tan, Wen-Ping Lv, Zhe Liu, Jian-Ping Zeng and Jia-Hong Dong
Funding Agency and Grant Number
Funding Agency Grant Number
Chinese Ministry of Health 200802012
National Natural Science Foundation of China 81271738
National Science and Technology Major Project of China 2012BAI06B01
Corresponding Author Jia-Hong Dong, MD, PhD, FACS, Department of Hepatobiliary Surgery, the Chinese PLA General Hospital, Beijing, China. dongjh_301@163.com
Key Words Portal flow; Portal diversion; Small-for-size syndrome; Mesocaval shunt
Core Tip We established a model of small-for-size syndrome in pigs undergoing 85%-90% hepatectomy with mesocaval shunt (MCS) placement to define the optimal portal inflow required to preserve liver regeneration. Our findings indicate that diversion of portal inflow by MCS reduces injury from portal overflow following major hepatectomy, whereas excessive diversion of portal flow can retard liver regeneration. Preservation of portal inflow to at least 3.2 times above baseline levels appeared to promote hepatocyte hypertrophy and reduce apoptosis.
Publish Date 2014-01-26 20:08
Citation Wang XQ, Xu YF, Tan JW, Lv WP, Liu Z, Zeng JP, Dong JH. Portal inflow preservation during portal diversion in small-for-size syndrome. World J Gastroenterol 2014; 20(4): 1021-1029
URL http://www.wjgnet.com/1007-9327/full/v20/i4/1021.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i4.1021
Full Article (PDF) WJG-20-1021.pdf
Full Article (Word) WJG-20-1021.doc
Manuscript File 3042-Review.doc
Answering Reviewers 3042-Answering reviewers.pdf
Copyright License Agreement 3042-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 3042-Language certificate.pdf
Peer-review Report 3042-Peer review.pdf
Scientific Editor Work List 3042-Scientific editor work list.doc