Publication Name	World Journal of Gastroenterology
Manuscript ID	32421
Country	Argentina

Received	2017-01-07 09:26
Peer-Review Started	2017-01-09 09:08
To Make the First Decision	2017-02-09 13:45
Return for Revision	2017-02-16 17:33
Revised	2017-03-01 23:59
Second Decision	2017-03-28 16:48
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2017-03-31 08:03
Articles in Press	2017-03-31 08:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-04-14 11:07
Publish the Manuscript Online	2017-04-28 10:26

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Biochemistry & Molecular Biology
Manuscript Type	Review
Article Title	Oxidative stress, antioxidants and intestinal calcium absorption
Manuscript Source	Invited Manuscript
All Author List	Gabriela Diaz de Barboza, Solange Guizzardi, Luciana Moine and Nori Tolosa de Talamoni
Funding Agency and Grant Number
Corresponding Author	Dr. Nori Tolosa de Talamoni, Professor, Laboratorio “Dr. Fernando Cañas”, Cátedra de Bioquímica y Biología Molecular, Facultad de Ciencias Médicas, INICSA (CONICET-Universidad Nacional de Córdoba), Pabellón Argentina, 2do. Piso, Ciudad Universitaria, Córdoba 5000, Argentina. ntolosatalamoni@yahoo.com.ar
Key Words	Transcellular and paracellular Ca2+pathways; DL-buthionine-S,R-sulfoximine; Menadione; Sodium deoxycholate; Lithocholic acid; Ursodeoxycholic acid; Melatonin
Core Tip	Glutathione depleting drugs inhibit the intestinal Ca2+ absorption by alteration in the protein expression and/or activity of molecules involved in the transcellular and paracellular Ca2+ pathways through mechanisms of oxidative stress, apoptosis and/or autophagy. Quercetin, melatonin, lithocholic and ursodeoxycholic acids block the effect of those drugs in experimental animals by their antioxidant, anti-apoptotic and anti-autophagic properties. Therefore, they may become drugs of choice for treatment of deteriorated intestinal Ca2+ absorption under oxidant conditions such as aging, diabetes, gut inflammation and other intestinal disorders.
Publish Date	2017-04-28 10:26
Citation	Diaz de Barboza G, Guizzardi S, Moine L, Tolosa de Talamoni N. Oxidative stress, antioxidants and intestinal calcium absorption. World J Gastroenterol 2017; 23(16): 2841-2853
URL	http://www.wjgnet.com/1007-9327/full/v23/i16/2841.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i16.2841

Full Article (PDF)	WJG-23-2841.pdf
Full Article (Word)	WJG-23-2841.doc
Manuscript File	32421-Review.doc
Answering Reviewers	32421-Answering reviewers.pdf
Audio Core Tip	32421-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	32421-Conflict-of-interest statement.pdf
Copyright License Agreement	32421-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	32421-Language certificate.pdf
Peer-review Report	32421-Peer-review(s).pdf
Scientific Misconduct Check	32421-Scientific misconduct check.pdf
Scientific Editor Work List	32421-Scientific editor work list.pdf