Publication Name	World Journal of Gastroenterology
Manuscript ID	3287
Country	Türkiye

Received	2013-04-20 11:48
Peer-Review Started	2013-04-21 18:30
To Make the First Decision	2013-05-23 17:18
Return for Revision	2013-05-24 10:45
Revised	2013-06-12 15:56
Second Decision	2013-07-05 11:53
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-07-05 12:57
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-08-28 17:26
Typeset the Manuscript	2013-09-10 20:15
Publish the Manuscript Online	2013-10-18 17:02

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Isolation and biochemical analysis of vesicles from taurohyodeoxycholic acid-infused isolated perfused rat livers
Manuscript Source	Invited Manuscript
All Author List	Adnan Adil Hismiogullari, Sahver Ege Hismiogullari and Khalid Rahman
Funding Agency and Grant Number
Corresponding Author	Dr. Adnan Adil Hismiogullari, Department of Medical Biochemistry, School of Medicine, The University of Balikesir, Cagis Yerleskesi, 10145 Balikesir, Turkey. ahismiogullari@gmail.com
Key Words	Taurohyodeoxycholic acid; Phospholipids; Biliary cholesterol; Bile; Vesicles
Core Tip	Bile contains various constituents including cholesterol and phospholipid, mainly phosphatidylcholine with a unique fatty acid composition of 1-palmitoyl 2-linoleyl (16:0-18:2) phosphatidylcholine and 1-palmitoyl 2-oleoyl (16:0-18:1). These biliary lipids are transported in vesicles from a specific intra-hepatic pool and an increase in biliary lipid-carrying vesicles may have implications for hepatic diseases such as gallstone formation. Taurohyodeoxycholic acid (THDC) stimulates the secretion of biliary phospholipids; hence THDC-infused rat livers were subjected to ultracentrifugation in order to isolate these phospholipid-carrying vesicles. The isolation of these biliary lipid-carrying vesicles was not successful; however, vesicles enriched in PDE activity were obtained.
Publish Date	2013-10-18 17:02
Citation	Hismiogullari AA, Hismiogullari SE, Rahman K. Isolation and biochemical analysis of vesicles from taurohyodeoxycholic acid-infused isolated perfused rat livers. World J Gastroenterol 2013; 19(37): 6228-6236
URL	http://www.wjgnet.com/1007-9327/full/v19/i37/6228.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i37.6228

Full Article (PDF)	WJG-19-6228.pdf
Manuscript File	3287-Review.doc
Answering Reviewers	3287-Answering reviewers.pdf
Copyright License Agreement	3287-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	3287-Language certificate.pdf
Peer-review Report	3287-Peer reviews.pdf
Scientific Editor Work List	3287-Scientific editor work list.doc