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Articles Published Processes
9/27/2018 9:38:46 AM | Browse: 922 | Download: 814
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Received |
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2018-03-30 00:06 |
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Peer-Review Started |
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2018-03-30 05:59 |
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To Make the First Decision |
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2018-05-11 01:10 |
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Return for Revision |
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2018-05-15 00:47 |
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Revised |
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2018-05-25 20:49 |
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Second Decision |
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2018-06-29 14:58 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2018-06-30 23:04 |
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Articles in Press |
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2018-06-30 23:04 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-09-24 06:14 |
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Publish the Manuscript Online |
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2018-09-27 09:38 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Hepatocellular carcinoma occurrence in DAA-treated hepatitis C virus patients: Correlated or incidental? A brief review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Eleni Gigi, Vasileios I Lagopoulos and Eleni Bekiari |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Eleni Gigi, MD, PhD, Academic Research, Assistant Professor, Hepatology Unit, 2nd Internal Medicine Department, Aristotle University Medical School, Hippokrateio General Hospital, Konstantinoupoleos 49, Thessaloniki 54642, Greece. elengigi@auth.gr |
| Key Words |
Hepatocellular carcinoma; Hepatitis C virus infection; Direct antiviral agents; Liver carcinogenesis; advanced fibrosis; Hepatitis C virus-induced cancer sequence; Sustained virological response |
| Core Tip |
Inability to reach sustained virological response (SVR) and cirrhosis are independent prognostic factors for developing hepatocellular carcinoma (HCC) in hepatitis C virus (HCV) patients from the interferon (IFN) era. DAAs offer significantly better SVR rates. The first data regarding HCC occurrence after direct antiviral agent (DAA) treatment are similar to the data from patients who achieved SVR under IFN treatment. Some reports on early HCC occurrence or recurrence after DAA treatment are probably due to selection bias, as they were not reproduced in large comparative studies. DAAs can eradicate HCV, but they cannot terminate HCV-induced premalignant processes once triggered. |
| Publish Date |
2018-09-27 09:38 |
| Citation |
Gigi E, Lagopoulos VI, Bekiari E. Hepatocellular carcinoma occurrence in DAA-treated hepatitis C virus patients: Correlated or incidental? A brief review. World J Hepatol 2018; 10(9): 595-602 |
| URL |
http://www.wjgnet.com/1948-5182/full/v10/i9/595.htm |
| DOI |
http://dx.doi.org/10.4254/wjh.v10.i9.595 |
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