| Category |
Medical Informatics |
| Manuscript Type |
Autobiography |
| Article Title |
Verification of gene expression profiles for colorectal cancer using 12 internet public microarray datasets
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Yu-Tien Chang, Chung-Tay Yao, Sui-Lung Su, Yu-Ching Chou, Chi-Ming Chu, Chi-Shuan Huang, Harn-Jing Terng, Hsiu-Ling Chou, Thomas Wetter, Kang-Hua Chen, Chi-Wen Chang, Yun-Wen Shih and Ching-Huang Lai |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Chi-Ming Chu, PhD, Professor, Division of Biomedical Statistics and Informatics, School of Public Health, National Defense Medical Center, No. 161, Section 6, Min-Chuan East Road, Taipei 114, Taiwan. chuchiming@web.de |
| Key Words |
Gene expression profiles; Colorectal cancer; Microarray; Gene Expression Omnibus; Gene Expression Omnibus; Gene Expression Omnibus series |
| Core Tip |
In the future, the 7-gene (CPEB4, EIF2S3, MGC20553, MS4A1, ANXA3, TNFAIP6 and IL2RB) logistic regression model that showed the best results can be further verified for more samples. Meanwhile, the causal relations are needed to confirm among the selected genes and colorectal cancer (CRC). The expression signature of these CRC-associated genes can be evaluated for early detection of CRC. Early detection can thus improve survival in patients before symptoms are detectable, during treatment, or during remission. |
| Publish Date |
2014-12-18 17:08 |
| Citation |
Chang YT, Yao CT, Su SL, Chou YC, Chu CM, Huang CS, Terng HJ, Chou HL, Wetter T, Chen KH, Chang CW, Shih YW, Lai CH. Verification of gene expression profiles for colorectal cancer using 12 internet public microarray datasets. World J Gastroenterol 2014; 20(46): 17476-17482 |
| URL |
http://www.wjgnet.com/1007-9327/full/v20/i46/17476.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v20.i46.17476 |
