| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Autobiography |
| Article Title |
Clinical significance of serum procalcitonin in patients with ulcerative colitis
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Shigeo Koido, Toshifumi Ohkusa, Kazuki Takakura, Shunichi Odahara, Shintaro Tsukinaga, Toyokazu Yukawa, Jimi Mitobe, Mikio Kajihara, Kan Uchiyama, Hiroshi Arakawa and Hisao Tajiri |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Grants-in-Aid for Scientific Research (C) from the Ministry of Education, Culture, Sports, Science and Technology of Japan |
23501289 |
|
| Corresponding Author |
Shigeo Koido, MD, Division of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University School of Medicine, 163-1 Kashiwa-shita, Kashiwa, Chiba 277-8567, Japan. shigeo_koido@jikei.ac.jp |
| Key Words |
C-reactive protein; Disease activity; Procalcitonin; Severity; Ulcerative colitis |
| Core Tip |
To investigate the association of procalcitonin (PCT) with ulcerative colitis (UC) activity, we analyzed 18 UC patients (7 with severe and 11 with mild-to-moderate UC) and 11 healthy volunteers. Serum PCT levels in severe UC patients were significantly higher than in mild-to-moderate UC patients and healthy volunteers. Moreover, patients with a Mayo endoscopic subscore of 3 points displayed significantly increased serum PCT levels compared with patients with a subscore of 2 points. However, serum C-reactive protein was not associated with disease activity or the Mayo endoscopic score. Thus, serum PCT may be a good biomarker for assessing UC activity. |
| Publish Date |
2013-12-18 10:39 |
| Citation |
Koido S, Ohkusa T, Takakura K, Odahara S, Tsukinaga S, Yukawa T, Mitobe J, Kajihara M, Uchiyama K, Arakawa H, Tajiri H. Clinical significance of serum procalcitonin in patients with ulcerative colitis. World J Gastroenterol 2013; 19(45): 8335-8341 |
| URL |
http://www.wjgnet.com/1007-9327/full/v19/i45/8335.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v19.i45.8335 |
