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6/21/2021 6:41:08 AM | Browse: 393 | Download: 822
Publication Name World Journal of Clinical Oncology
Manuscript ID 60168
Country Italy
Received
2020-10-23 11:11
Peer-Review Started
2020-10-23 11:12
To Make the First Decision
Return for Revision
2020-12-04 16:08
Revised
2020-12-24 17:29
Second Decision
2021-03-03 06:40
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-03-03 16:50
Articles in Press
2021-03-03 16:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-04-15 15:14
Typeset the Manuscript
2021-05-31 08:58
Publish the Manuscript Online
2021-06-21 06:41
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Case Report
Article Title Long term complete response in metastatic poorly-differentiated neuroendocrine rectal carcinoma with multimodal approach: A case report
Manuscript Source Unsolicited Manuscript
All Author List Silvia Della Torre, Germana de Nucci, Pietro Maria Lombardi, Samuele Grandi, Gianpiero Manes and Roberto Bollina
ORCID
Author(s) ORCID Number
Silvia Della Torre http://orcid.org/0000-0003-3840-7888
Germana de Nucci http://orcid.org/0000-0001-8758-654X
Pietro Maria Lombardi http://orcid.org/0000-0002-2633-7977
Samuele Grandi http://orcid.org/0000-0002-9570-240X
Gianpiero Manes http://orcid.org/0000-0002-5319-588X
Roberto Bollina http://orcid.org/0000-0003-0714-9337
Funding Agency and Grant Number
Corresponding Author Silvia Della Torre, MD, Doctor, Oncology Unit, Asst Rhodesien, Corso Europa 2, Rho 20017, Italy. sdellatorre@asst-rhodense.it
Key Words neuroendocrine tumor; multimodal therapy; case report; rectal carcinoma; surgery; radiotherapy
Core Tip Neuroendocrine gastrointestinal tumors are rare with different clinical behaviors. Prognostic factors are tumor differentiation, Ki-67 index and presence of distant metastases. Most of them are well differentiated neuroendocrine tumors with a good prognosis and a 5-year overall survival of 60–90%. Surgery is the gold standard treatment in local and metastatic disease, while radiotherapy is ineffective. Poorly differentiated neuroendocrine carcinomas (NECs) represent only 5–10% among digestive NETS. Here we describe a rare case of a patient with a diagnosis of poorly differentiated rectal metastatic NEC treated with a different treatment approach and with a complete remission (CR) after 5 years.
Publish Date 2021-06-21 06:41
Citation Della Torre S, de Nucci G, Lombardi PM, Grandi S, Manes G, Bollina R. Long-term complete response in metastatic poorly-differentiated neuroendocrine rectal carcinoma with a multimodal approach: A case report. World J Clin Oncol 2021; 12(6): 500-506
URL https://www.wjgnet.com/2218-4333/full/v12/i6/500.htm
DOI https://dx.doi.org/10.5306/wjco.v12.i6.500
Full Article (PDF) WJCO-12-500.pdf
Full Article (Word) WJCO-12-500.docx
Manuscript File 60168_Auto_Edited_LM-Webster J-Clear.docx
Answering Reviewers 60168-Answering reviewers.pdf
Audio Core Tip 60168-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 60168-Conflict-of-interest statement.pdf
Copyright License Agreement 60168-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 60168-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 60168-Language certificate.pdf
Peer-review Report 60168-Peer-review(s).pdf
Scientific Misconduct Check 60168-CrossCheck.png
Scientific Misconduct Check 60168-Bing-Gong ZM-1.png
Scientific Misconduct Check 60168-Scientific misconduct check.pdf
Scientific Editor Work List 60168-Scientific editor work list.pdf