Publication Name	World Journal of Diabetes
Manuscript ID	60901
Country	China

Received	2021-02-23 09:28
Peer-Review Started	2021-02-23 09:28
To Make the First Decision
Return for Revision	2021-03-30 02:21
Revised	2021-04-09 11:00
Second Decision	2021-07-12 03:37
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-07-12 09:56
Articles in Press	2021-07-12 09:56
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-07-23 06:05
Typeset the Manuscript	2021-08-04 07:04
Publish the Manuscript Online	2021-08-09 10:25

ISSN	1948-9358 (online)
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Category	Endocrinology & Metabolism
Manuscript Type	Observational Study
Article Title	Polymorphisms in HIF-1a gene are not associated with diabetic retinopathy in China
Manuscript Source	Unsolicited Manuscript
All Author List	Yue-Hong Liu, Chang Guo, Yi-Qiong Sun and Qiang Li
ORCID	Author(s) ORCID Number Yue-Hong Liu http://orcid.org/0000-0002-6981-0605 Chang Guo http://orcid.org/0000-0002-9591-757X Yi-Qiong Sun http://orcid.org/0000-0003-0470-8666 Qiang Li http://orcid.org/0000-0002-6306-9561
Funding Agency and Grant Number
Corresponding Author	Qiang Li, MD, PhD, Chief Physician, Department of Endocrinology, The Second Affiliated Hospital of Harbin Medical University, No. 246 Xuefu Road, Nangang District, Harbin 150086, Heilongjiang Province, China. qianglisz@163.com
Key Words	Diabetic retinopathy; Single nucleotide polymorphisms; HIF1a; Vascular endothelial growth factor; Diabetes; Mutation
Core Tip	Vascular endothelial growth factor (VEGF), a potent endothelial cell mitogen, plays a crucial role in neovascularization of proliferative diabetic retinopathy (DR). The human VEGF gene encoding VEGF was identified to be the first target genes of hypoxia-inducible factor-1 (HIF-1). Therefore, HIF-1a is supposed to be involved in pathology of DR. Here, investigate whether the polymorphisms in HIF-1a gene are associated with DR.
Publish Date	2021-08-09 10:25
Citation	Liu YH, Guo C, Sun YQ, Li Q. Polymorphisms in HIF-1a gene are not associated with diabetic retinopathy in China. World J Diabetes 2021; 12(8): 1304-1311
URL	https://www.wjgnet.com/1948-9358/full/v12/i8/1304.htm
DOI	https://dx.doi.org/10.4239/wjd.v12.i8.1304

Full Article (PDF)	WJD-12-1304.pdf
Full Article (Word)	WJD-12-1304.docx
Manuscript File	60901-Review-Filipodia.docx
Answering Reviewers	60901-Answering reviewers.pdf
Audio Core Tip	60901-Audio core tip.m4a
Biostatistics Review Certificate	60901-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	60901-Conflict-of-interest statement.pdf
Copyright License Agreement	60901-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	60901-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	60901-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	60901-Language certificate.pdf
Peer-review Report	60901-Peer-review(s).pdf
Scientific Misconduct Check	60901-Bing-Wang JL-1.jpg
Scientific Misconduct Check	60901-Scientific misconduct check.pdf
Scientific Editor Work List	60901-Scientific editor work list.pdf