| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Cost-effective screening using a two-antibody panel for detecting mismatch repair deficiency in sporadic colorectal cancer
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Jong Beom Kim, Young Il Kim, Yong Sik Yoon, Jihun Kim, Seo Young Park, Jong Lyul Lee, Chan Wook Kim, In Ja Park, Seok-Byung Lim, Chang Sik Yu and Jin Cheon Kim |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Asian Institute for Life Sciences, Asian Medical Center, Seoul, South Korea |
2020IP0039 |
|
| Corresponding Author |
Yong Sik Yoon, MD, PhD, Professor, Division of Colon and Rectal Surgery, University of Ulsan College of Medicine, Asan Medical Center, 88, Olympic-ro 43-gil, Songpa-gu, Seoul 05505, South Korea. yoonys@amc.seoul.kr |
| Key Words |
Adenocarcinoma; DNA mismatch repair; Immunochemistry; Monoclonal antibody; Microsatellite instability; Cost-effectiveness |
| Core Tip |
Screening for mismatch repair deficiency in sporadic colorectal cancer has not been established. This study compared microsatellite instability test to four- and two types of two-antibody panels of immunohistochemistry. A two-antibody panel of PMS2/MSH6 may be the best choice in terms of balancing cost-effectiveness and accuracy for screening. |
| Publish Date |
2021-08-24 02:07 |
| Citation |
Kim JB, Kim YI, Yoon YS, Kim J, Park SY, Lee JL, Kim CW, Park IJ, Lim SB, Yu CS, Kim JC. Cost-effective screening using a two-antibody panel for detecting mismatch repair deficiency in sporadic colorectal cancer. World J Clin Cases 2021; 9(24): 6999-7008 |
| URL |
https://www.wjgnet.com/2307-8960/full/v9/i24/6999.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v9.i24.6999 |
