Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	6286
Country	United States

Received	2013-10-11 21:23
Peer-Review Started	2013-10-12 15:51
To Make the First Decision	2013-10-28 16:11
Return for Revision	2013-11-01 11:45
Revised	2013-11-05 23:47
Second Decision	2013-11-15 19:05
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-11-16 01:43
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-12-10 11:21
Publish the Manuscript Online	2013-12-17 09:59

ISSN	1948-5204 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Surgery
Manuscript Type	Review
Article Title	Surgery for colorectal liver metastases: The evolution of determining prognosis
Manuscript Source	Invited Manuscript
All Author List	Gaya Spolverato, Aslam Ejaz, Nilo Azad and Timothy M Pawlik
Funding Agency and Grant Number
Corresponding Author	Timothy M Pawlik, MD, MPH, PhD, FACS, Professor, Department of Surgery, The Johns Hopkins Hospital, 600 N. Wolfe Street, Blalock 688, Baltimore, MD 21287, United States. tpawlik1@jhmi.edu
Key Words	Colorectal; Metastasis; Prognosis; Risk score; Molecular markers; Outcomes
Core Tip	Historically, prognosis after resection has been largely assessed based on preoperative clinicopathologic features. Data validating the prognostic value of patient and tumor specific factors have been mixed, with many recent studies showing these scoring systems to correlate poorly with survival. Rather, there has been an emerging interest in biological or molecular markers of prognosis to more effectively assess patient prognosis after resection of colorectal liver metastasis. In this review, we discuss past, present, and possible future markers of prognosis among colorectal cancer patients with liver metastasis undergoing resection with curative intent.
Publish Date	2013-12-17 09:59
Citation	Spolverato G, Ejaz A, Azad N, Pawlik TM. Surgery for colorectal liver metastases: The evolution of determining prognosis. World J Gastrointest Oncol 2013; 5(12): 207-221
URL	http://www.wjgnet.com/1948-5204/full/v5/i12/207.htm
DOI	http://dx.doi.org/10.4251/wjgo.v5.i12.207

Full Article (PDF)	WJGO-5-207.pdf
Full Article (Word)	WJGO-5-207.doc
Manuscript File	6286-Review.docx
Answering Reviewers	6286-Answering reviewers.pdf
Copyright License Agreement	6286-Copyright assignment.pdf
Peer-review Report	6286-Peer review(s).pdf
Scientific Editor Work List	6286-Scientific editor work list.doc