Publication Name	World Journal of Gastroenterology
Manuscript ID	6320
Country	Belgium

Received	2013-10-13 22:53
Peer-Review Started	2013-10-15 13:48
To Make the First Decision	2013-11-13 15:33
Return for Revision	2013-11-14 16:03
Revised	2013-12-24 23:41
Second Decision	2014-01-08 18:14
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-01-08 18:38
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-05-19 13:43
Publish the Manuscript Online	2014-06-21 13:56

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Role of autophagy in the pathophysiology of nonalcoholic fatty liver disease: A controversial issue
Manuscript Source	Invited Manuscript
All Author List	Wilhelmus J Kwanten, Wim Martinet, Peter P Michielsen and Sven M Francque
Funding Agency and Grant Number	Funding Agency Grant Number Scientific Research (FWO) - Flanders 11J9513N Scientific Research (FWO) - Flanders G007412N Scientific Research (FWO) - Flanders G044312N Scientific Research (FWO) - Flanders 1802514N
Corresponding Author	Sven M Francque, MD, PhD, Department of Gastroenterology Hepatology, Antwerp University Hospital, Wilrijkstraat 10, B-2650 Edegem, Province of Antwerp, Belgium. sven.francque@uza.be
Key Words	Non-alcoholic fatty liver disease; Non-alcoholic fatty liver disease; Steatohepatitis; Non-alcoholic steatohepatitis; Autophagy; Lipophagy; Lipid metabolism
Core Tip	Autophagy is a mechanism involved in cellular homeostasis. In this review the current knowledge on the role of autophagy in non-alcoholic fatty liver disease (NAFLD) is summarised, with emphasis on the current controversy on the lipolytic vs lipogenic function in hepatic lipid metabolism. Furthermore the role of autophagy in the pathophysiology of insulin resistance, hepatocellular injury and fibrogenesis is reviewed to better understand its importance in NAFLD.
Publish Date	2014-06-21 13:56
Citation	Kwanten WJ, Martinet W, Michielsen PP, Francque SM. Role of autophagy in the pathophysiology of nonalcoholic fatty liver disease: A controversial issue. World J Gastroenterol 2014; 20(23): 7325-7338
URL	http://www.wjgnet.com/1007-9327/full/v20/i23/7325.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i23.7325

Full Article (PDF)	WJG-20-7325.pdf
Full Article (Word)	WJG-20-7325.doc
Manuscript File	6320-Review.docx
Answering Reviewers	6320_Answering_Reviewers.docx
Copyright License Agreement	6320_BPG_Copyright_Assignment.pdf
Non-Native Speakers of English Editing Certificate	BDW_DiplomaInteruniversityTestofAcademicEnglish.pdf