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8/28/2014 9:54:00 AM | Browse: 871 | Download: 740
Publication Name World Journal of Gastroenterology
Manuscript ID 6335
Country China
Received
2013-10-18 16:48
Peer-Review Started
2013-10-22 10:26
To Make the First Decision
2014-01-12 11:03
Return for Revision
2014-01-12 13:27
Revised
Second Decision
2014-03-06 18:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-03-06 18:05
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-04-09 15:31
Typeset the Manuscript
2014-04-28 18:13
Publish the Manuscript Online
2014-05-14 10:58
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Autobiography
Article Title Use of lectin microarray to differentiate gastric cancer from gastric ulcer
Manuscript Source Invited Manuscript
All Author List Wei-Li Huang, Yang-Guang Li, Yong-Chen Lv, Xiao-Hui Guan, Hui-Fan Ji and Bao-Rong Chi
Funding Agency and Grant Number
Corresponding Author Bao-Rong Chi, MD, PhD, Professor, Department of Hepatology, the First Clinic Hospital of Jilin University, No. 71 Xinmin Dajie, Changchun 130021, Jilin Province, China. chibr@jlu.edu.cn
Key Words Gastric cancer; Gastric ulcer; Lectin microarray; Lectin histochemistry; Differentiate
Core Tip To assess the different glycopatterns in gastric ulcer and cancer by lectin microarray, which was then validated by lectin histochemistry. The results showed that the glycosylation level of gastric cancer was significantly higher than that in ulcer; the subsequent validation with two lectins (MPL and VVA) using lectin histochemistry showed higher positive rates and signal intensity in all types of gastric cancer detected, when compared with ulcer, which was consistent with the results of the lectin microarray, suggesting that GalNAc bound by the lectins MPL and VVA could be used to distinguish gastric cancer from ulcer.
Publish Date 2014-05-14 10:58
Citation Huang WL, Li YG, Lv YC, Guan XH, Ji HF, Chi BR. Use of lectin microarray to differentiate gastric cancer from gastric ulcer. World J Gastroenterol 2014; 20(18): 5474-5482
URL http://www.wjgnet.com/1007-9327/full/v20/i18/5474.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i18.5474
Full Article (PDF) WJG-20-5474.pdf
Full Article (Word) WJG-20-5474.doc
Manuscript File 6335-Review.doc
Answering Reviewers 6335-Answering reviewers.pdf
Copyright License Agreement 6335-Copyright assignment.pdf
Peer-review Report 6335-Peer reviews.pdf
Scientific Editor Work List 6335-Scientific editor work list.doc