Publication Name	World Journal of Diabetes
Manuscript ID	63566
Country	Italy

Received	2021-01-29 10:31
Peer-Review Started	2021-01-29 10:33
To Make the First Decision
Return for Revision	2021-03-01 01:09
Revised	2021-03-17 15:29
Second Decision	2021-05-22 14:44
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-05-22 15:16
Articles in Press	2021-05-22 15:16
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-06-12 21:28
Typeset the Manuscript	2021-07-07 07:02
Publish the Manuscript Online	2021-07-12 05:45

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Endocrinology & Metabolism
Manuscript Type	Review
Article Title	Mechanisms of altered bone remodeling in children with type 1 diabetes
Manuscript Source	Invited Manuscript
All Author List	Giacomina Brunetti, Gabriele D'Amato, Stefania De Santis, Maria Grano and Maria Felicia Faienza
ORCID	Author(s) ORCID Number Giacomina Brunetti http://orcid.org/0000-0002-0681-1432 Gabriele D'Amato http://orcid.org/0000-0001-5160-9340 Stefania De Santis http://orcid.org/0000-0001-6877-2208 Maria Grano http://orcid.org/0000-0002-7121-5899 Maria Felicia Faienza http://orcid.org/0000-0002-1899-8337
Funding Agency and Grant Number
Corresponding Author	Giacomina Brunetti, PhD, Academic Research, Department of Biosciences, Biotechnologies and Biopharmaceutics, University "A. Moro" of Bari, Piazza Giulio Cesare 11, Bari 70124, Italy. giacomina.brunetti@uniba.it
Key Words	Type 1 diabetes; Children; Bone remodeling; Osteoclasts; Osteoblasts
Core Tip	Bone fragility is a well-known complication related to type 1 diabetes mellitus, which can manifest as from the disease onset, already in childhood. The mechanisms underlying this relationship, and the precise role of metabolic control in preventing bone impairment, are not yet fully understood. Future studies are needed to better clarify the factors responsible for bone damage in diabetic subjects, and to identify strategies for avoiding and managing osteopenia/osteoporosis in these subjects.
Publish Date	2021-07-12 05:45
Citation	Brunetti G, D'Amato G, De Santis S, Grano M, Faienza MF. Mechanisms of altered bone remodeling in children with type 1 diabetes. World J Diabetes 2021; 12(7): 997-1009
URL	https://www.wjgnet.com/1948-9358/full/v12/i7/997.htm
DOI	https://dx.doi.org/10.4239/wjd.v12.i7.997

Full Article (PDF)	WJD-12-997.pdf
Full Article (Word)	WJD-12-997.docx
Manuscript File	63566-Review-FilipodiaCL.docx
Answering Reviewers	63566-Answering reviewers.pdf
Audio Core Tip	63566-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	63566-Conflict-of-interest statement.pdf
Copyright License Agreement	63566-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	63566-Language certificate.pdf
Peer-review Report	63566-Peer-review(s).pdf
Scientific Misconduct Check	63566-Bing-Ma YJ-1.jpg
Scientific Misconduct Check	63566-Bing-Liu M-2.png
Scientific Misconduct Check	63566-Scientific misconduct check.pdf
Scientific Editor Work List	63566-Scientific editor work list.pdf