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Articles Published Processes
12/30/2021 8:21:52 AM | Browse: 312 | Download: 466
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Received |
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2021-04-21 10:27 |
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Peer-Review Started |
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2021-04-21 10:30 |
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To Make the First Decision |
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Return for Revision |
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2021-06-13 21:25 |
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Revised |
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2021-06-25 11:57 |
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Second Decision |
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2021-11-24 03:35 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2021-11-25 01:46 |
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Articles in Press |
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2021-11-25 01:46 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-12-24 10:42 |
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Publish the Manuscript Online |
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2021-12-30 08:21 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Distribution of transient receptor potential vanilloid-1 channels in gastrointestinal tract of patients with morbid obesity
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Unal Atas, Nuray Erin, Gokhan Tazegul, Gulsum Ozlem Elpek and Bülent Yıldırım |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Gulsum Ozlem Elpek, MD, Professor, Research Assistant Professor, Department of Pathology, Akdeniz University Medical School, Dumlupınar Bulvarı, Antalya 07070, Türkiye. elpek@akdeniz.edu.tr |
| Key Words |
Capsaicin; Transient receptor potential vanilloid 1; Immunohistochemistry; Morbid obesity; Obesity; Transient receptor potential channels; Transient receptor potential vanilloid cation channels |
| Core Tip |
Capsaicin-associated pathways may provide an alternative approach for obesity treatment. Our results suggest that transient receptor potential vanilloid (TRPV1) activation can provide anti-obesity and gastroprotective activity. TRPV1 distribution in the gastric and duodenal mucosal cells of morbidly obese people is similar to that in patients with normal weight. Hence, drugs targeting TRPV1 may be an effective approach in these patients. Further studies are needed in this area. |
| Publish Date |
2021-12-30 08:21 |
| Citation |
Atas U, Erin N, Tazegul G, Elpek GO, Yıldırım B. Distribution of transient receptor potential vanilloid-1 channels in gastrointestinal tract of patients with morbid obesity. World J Clin Cases 2022; 10(1): 79-90 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i1/79.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i1.79 |
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