Publication Name	World Journal of Gastroenterology
Manuscript ID	6954
Country	Italy

Received	2013-10-31 08:07
Peer-Review Started	2013-11-01 10:45
To Make the First Decision	2014-01-24 13:19
Return for Revision	2014-01-25 14:21
Revised
Second Decision	2014-04-09 08:16
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-04-09 09:03
Articles in Press	2014-05-23 09:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-06-10 10:09
Publish the Manuscript Online	2014-06-27 10:37

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Surgery
Manuscript Type	Topic Highlights
Article Title	Palliative care and end-stage colorectal cancer management: The surgeon meets the oncologist
Manuscript Source	Invited Manuscript
All Author List	Renato Costi, Francesco Leonardi, Daniele Zanoni, Vincenzo Violi and Luigi Roncoroni
Funding Agency and Grant Number	Funding Agency Grant Number University of Parma Research Funds
Corresponding Author	Renato Costi, MD, PhD, FACS, Istituto di Clinica Chirurgica Generale e Terapia Chirurgica, Dipartimento di Scienze Chirurgiche, Università di Parma, Via Gramsci 14, 43100 Parma, Italy. renatocosti@hotmail.com
Key Words	Colorectal cancer; Palliative care; Multimodal treatment; Chemotherapy; Surgery; Stenting; Radiotherapy
Core Tip	Colorectal cancer is a common neoplasia with considerable morbidity/mortality. Every fifth patient presents with metastatic disease, which is usually not resectable. In asymptomatic patients, new chemotherapy regimens allow long survival and, potentially, conversion of non resectable liver metastasis in resectable ones, with a significantly improved prognosis. Obstruction is traditionally approached by colonic resection, stoma or internal by-pass, although nowadays stenting is a feasible option. Perforation is associated with the highest mortality and is mostly managed surgically, by lavage/drainage, colonic resection and/or stoma. Bleeding and other symptoms (pain, tenesmus) are managed mini-invasivally by radiotherapy, laser therapy and other transanal procedures.
Publish Date	2014-06-27 10:37
Citation	Costi R, Leonardi F, Zanoni D, Violi V, Roncoroni L. palliative care and end-stage colorectal cancer management: The surgeon meets the oncologist. World J Gastroenterol 2014; 20(24): 7602-7621
URL	http://www.wjgnet.com/1007-9327/full/v20/i24/7602.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i24.7602

Full Article (PDF)	WJG-20-7602.pdf
Full Article (Word)	WJG-20-7602.doc
Manuscript File	6954-Review.docx
Answering Reviewers	6954-Answering reviewers.pdf
Copyright License Agreement	6954-Copyright assignment.pdf
Peer-review Report	6954-Peer review(s).pdf
Scientific Editor Work List	6954-Scientific editor work list.doc