| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical and Translational Research |
| Article Title |
Association and prognostic significance of alpha-L-fucosidase-1 and matrix metalloproteinase 9 expression in esophageal squamous cell carcinoma
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xiang-Yang Yu, Sheng-Cheng Lin, Meng-Qi Zhang, Xiao-Tong Guo, Kai Ma, Li-Xu Wang, Wen-Ting Huang, Zhe Wang, Xin Yu, Chun-Guang Wang, Lan-Jun Zhang and Zhen-Tao Yu |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Shenzhen Key Medical Discipline Construction Fund |
SZXK075 |
| the Sanming Project of Medicine in Shenzhen |
SZSM201612097 |
|
| Corresponding Author |
Zhen-Tao Yu, MD, PhD, Surgical Oncologist, Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 113 Baohe Avenue, Longgang District, Shenzhen 518116, Guangdong Province, China. yztao2015@163.com |
| Key Words |
Esophageal squamous cell carcinoma; Alpha-L-fucosidase-1; Matrix metalloproteinase-9; Immunohistochemistry |
| Core Tip |
Our results demonstrated that high alpha-L-fucosidase-1 (FUCA1) expression was significantly associated with a worse overall survival, which illustrated that FUCA1 may have the ability to promote tumor cell invasion and metastasis among patients with esophageal squamous cell carcinoma (ESCC). Moreover, this study provides additional evidence that the molecular mechanisms of FUCA1 in ESCC are entirely different. |
| Publish Date |
2022-02-10 14:26 |
| Citation |
Yu XY, Lin SC, Zhang MQ, Guo XT, Ma K, Wang LX, Huang WT, Wang Z, Yu X, Wang CG, Zhang LJ, Yu ZT. Association and prognostic significance of alpha-L-fucosidase-1 and matrix metalloproteinase 9 expression in esophageal squamous cell carcinoma. World J Gastrointest Oncol 2022; 14(2): 498-510 |
| URL |
https://www.wjgnet.com/1948-5204/full/v14/i2/498.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v14.i2.498 |
