Publication Name	World Journal of Clinical Cases
Manuscript ID	70613
Country	China

Received	2021-08-10 11:07
Peer-Review Started	2021-08-10 11:12
To Make the First Decision
Return for Revision	2021-12-01 09:19
Revised	2021-12-06 14:19
Second Decision	2022-02-17 05:48
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-02-20 12:57
Articles in Press	2022-02-20 12:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-02-24 15:30
Publish the Manuscript Online	2022-03-22 14:35

ISSN	2307-8960 (online)
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Category	Oncology
Manuscript Type	Case Report
Article Title	Sarcomatoid intrahepatic cholangiocarcinoma with good patient prognosis after treatment with Huaier granules following hepatectomy: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Ji-Ye Feng, Xian-Peng Li, Zong-Yang Wu, Li-Ping Ying, Chang Xin, Zhen-Zhen Dai, Yao Shen and Yi-Feng Wu
ORCID	Author(s) ORCID Number Ji-Ye Feng http://orcid.org/0000-0002-4860-5530 Xian-Peng Li http://orcid.org/0000-0002-8047-4091 Zong-Yang Wu http://orcid.org/0000-0002-4178-5698 Li-Ping Ying http://orcid.org/0000-0003-3030-258X Chang Xin http://orcid.org/0000-0002-9690-8149 Zhen-Zhen Dai http://orcid.org/0000-0002-2751-1826 Yao Shen http://orcid.org/0000-0003-0281-3809 Yi-Feng Wu http://orcid.org/0000-0001-9437-3307
Funding Agency and Grant Number
Corresponding Author	Yi-Feng Wu, MD, PhD, Chief Doctor, Department of Hepatobiliary & Pancreas Surgery, the Affiliated People’s Hospital of Ningbo University, No. 251 Baizhang Road, Ningbo 315040, Zhejiang Province, China. wyf5495@163.com
Key Words	Sarcomatous intrahepatic cholangiocarcinoma; Hepatectomy; Huaier granules; Diagnose; Therapy; Case report
Core Tip	Sarcomatoid intrahepatic cholangiocarcinoma (SICC) is an extremely rare and highly invasive malignant tumor of the liver. The precise pathologic mechanism of SICC has not been clearly identified, and the prognosis is very poor. The effectiveness of the treatment strategy of radical hepatectomy combined with Huaier granules has not yet been reported. A 69-year-old male with long-term use of Huaier granules for anticancer therapy postoperation achieved long-term survival with no tumor recurrence or metastasis. We reported the first case of successful treatment with Huaier granules as an adjuvant treatment after surgery and demonstrated that Huaier granules are safe and effective.
Publish Date	2022-03-22 14:35
Citation	Feng JY, Li XP, Wu ZY, Ying LP, Xin C, Dai ZZ, Shen Y, Wu YF. Sarcomatoid intrahepatic cholangiocarcinoma with good patient prognosis after treatment with Huaier granules following hepatectomy: A case report. World J Clin Cases 2022; 10(9): 2829-2835
URL	https://www.wjgnet.com/2307-8960/full/v10/i9/2829.htm
DOI	https://dx.doi.org/10.12998/wjcc.v10.i9.2829

Full Article (PDF)	WJCC-10-2829.pdf
Full Article (Word)	WJCC-10-2829.docx
Manuscript File	70613_Auto_Edited.docx
Answering Reviewers	70613-Answering reviewers.pdf
Audio Core Tip	70613-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	70613-Conflict-of-interest statement.pdf
Copyright License Agreement	70613-Copyright license agreement.pdf
Signed Consent for Treatment Form(s) or Document(s)	70613-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	70613-Language certificate.pdf
Peer-review Report	70613-Peer-review(s).pdf
Scientific Misconduct Check	70613-Bing-Fan JR-2.png
Scientific Editor Work List	70613-Scientific editor work list.pdf