Publication Name	World Journal of Gastroenterology
Manuscript ID	7119
Country	Germany

Received	2013-11-05 11:10
Peer-Review Started	2013-11-05 17:17
To Make the First Decision	2013-11-21 20:43
Return for Revision	2013-12-02 17:03
Revised	2013-12-23 11:33
Second Decision	2014-04-16 11:17
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-04-16 12:13
Articles in Press	2014-05-23 10:59
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-05-14 08:30
Typeset the Manuscript	2014-08-23 19:38
Publish the Manuscript Online	2014-09-07 13:31

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Virology
Manuscript Type	Topic Highlights
Article Title	Control of hepatitis B virus replication by interferons and Toll-like receptor signaling pathways
Manuscript Source	Invited Manuscript
All Author List	Rong-Juan Pei, Xin-Wen Chen and Meng-Ji Lu
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 31200135 (to Pei RJ and Chen XC) National Natural Science Foundation of China 31200699 (to Pei RJ and Chen XC) German Research Foundation TRR60 (to Lu MG) German Research Foundation GK1045/2 (to Lu MG) German Research Foundation GK1949 (to Lu MG)
Corresponding Author	Meng-Ji Lu, Professor, Institute of Virology, University Hospital of Essen, Hufelandstrasse 55, 45122 Essen, Germany. mengji.lu@uni-due.de
Key Words	Hepatitis B virus; Interferon; Toll-like receptor; Interferon stimulated genes; Innate immune response
Core Tip	Hepatitis B virus (HBV) infection is one of the major causes of liver diseases affecting more than 350 million people worldwide. Interferon (IFN)- and Toll-like receptors (TLR)-mediated innate immune responses could restrict HBV replication at the different steps of viral life cycle. Though a great number of publications in this field appeared during the last years, there is no review to discuss the progress. Here, we summarized the currently available knowledge about the anti-HBV effect of IFNs and TLRs and the possible effectors downstream the IFN signaling pathway. This review provides an overview for scientists working on HBV and related fields.
Publish Date	2014-09-07 13:31
Citation	Pei RJ, Chen XW, Lu MJ. Control of hepatitis B virus replication by interferons and Toll-like receptor signaling pathways. World J Gastroenterol 2014; 20(33): 11618-11629
URL	http://www.wjgnet.com/1007-9327/full/v20/i33/11618.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i33.11618

Full Article (PDF)	WJG-20-11618.pdf
Full Article (Word)	WJG-20-11618.doc
Manuscript File	7119-Review.docx
Answering Reviewers	7119-Answering reviewers.pdf
Copyright License Agreement	7119-Copyright assignment.pdf
Peer-review Report	7119-Peer reviewer(s).pdf
Scientific Editor Work List	7119-Scientific editor work list.doc