Publication Name	World Journal of Hepatology
Manuscript ID	72023
Country	Japan

Received	2021-09-30 05:51
Peer-Review Started	2021-09-30 05:54
To Make the First Decision
Return for Revision	2021-12-04 12:11
Revised	2021-12-30 09:43
Second Decision	2022-02-28 05:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-03-06 23:51
Articles in Press	2022-03-06 23:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-03-22 08:40
Publish the Manuscript Online	2022-04-22 10:52

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Gravity assistance enables liver stiffness measurements to detect liver fibrosis under congestive circumstances
Manuscript Source	Unsolicited Manuscript
All Author List	Takeshi Suda, Ai Sugimoto, Tsutomu Kanefuji, Atsushi Abe, Takeshi Yokoo, Takahiro Hoshi, Satoshi Abe, Shinichi Morita, Kazuyoshi Yagi, Masashi Takahashi and Shuji Terai
ORCID	Author(s) ORCID Number Takeshi Suda http://orcid.org/0000-0002-8231-0883 Ai Sugimoto http://orcid.org/0000-0001-6526-7505 Tsutomu Kanefuji http://orcid.org/0000-0002-9782-2582 Atsushi Abe http://orcid.org/0000-0003-2908-9064 Takeshi Yokoo http://orcid.org/0000-0001-7138-1785 Takahiro Hoshi http://orcid.org/0000-0002-8990-5687 Satoshi Abe http://orcid.org/0000-0003-1153-0720 Shinichi Morita http://orcid.org/0000-0003-1608-3827 Kazuyoshi Yagi http://orcid.org/0000-0001-9427-3496 Masashi Takahashi http://orcid.org/0000-0001-7035-9578 Shuji Terai http://orcid.org/0000-0002-5439-635X
Funding Agency and Grant Number
Corresponding Author	Takeshi Suda, MD, PhD, Professor, Department of Gastroenterology and Hepatology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, 4132 Urasa, Minami Uonuma 949-7302, Niigata, Japan. tspitt@med.niigata-u.ac.jp
Key Words	Shear wave elastography; Inferior vena cava diameter; Congestive hepatopathy; Liver fibrosis; Body positions; Fibrosis-4 index
Core Tip	Medical progress ironically makes the liver a prognostic determinant in patients with congenital heart diseases because there are no effective biomarkers to evaluate pathological progression in congestive hepatopathy. A canonical liver stiffness measurement cannot screen for fibrous liver under congestion because congestion itself makes the liver stiff without fibrosis. Here, we report a simple strategy of liver stiffness measurement to identify clues to liver fibrosis even under congestion. The basic data presented in this report provide insights not only for the clinical application of liver stiffness in patients with congestive heart diseases but also for the physiological components and mechanisms underlying liver stiffness.
Publish Date	2022-04-22 10:52
Citation	Suda T, Sugimoto A, Kanefuji T, Abe A, Yokoo T, Hoshi T, Abe S, Morita S, Yagi K, Takahashi M, Terai S. Gravity assistance enables liver stiffness measurements to detect liver fibrosis under congestive circumstances. World J Hepatol 2022; 14(4): 778-790
URL	https://www.wjgnet.com/1948-5182/full/v14/i4/778.htm
DOI	https://dx.doi.org/10.4254/wjh.v14.i4.778

Full Article (PDF)	WJH-14-778.pdf
Full Article (Word)	WJH-14-778.docx
Manuscript File	72023_Auto_Edited.docx
Answering Reviewers	72023-Answering reviewers.pdf
Audio Core Tip	72023-Audio core tip.m4a
Biostatistics Review Certificate	72023-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	72023-Conflict-of-interest statement.pdf
Copyright License Agreement	72023-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	72023-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	72023-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	72023-Language certificate.pdf
Supplementary Material	72023-Supplementary material.pdf
Peer-review Report	72023-Peer-review(s).pdf
Scientific Misconduct Check	72023-Bing-Wang LL-2.png
Scientific Editor Work List	72023-Scientific editor work list.pdf