ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Retrospective Cohort Study |
Article Title |
Impact of sarcopenia on tumor response and survival outcomes in patients with hepatocellular carcinoma treated by trans-arterial (chemo)-embolization
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Gael Roth, Yann Teyssier, Maxime Benhamou, Mélodie Abousalihac, Stefano Caruso, Christian Sengel, Olivier Seror, Julien Ghelfi, Arnaud Seigneurin, Nathalie Ganne-Carrie, Elia Gigante, Lorraine Blaise, Olivier Sutter, Thomas Decaens and Jean-Charles Nault |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Jean-Charles Nault, MD, PhD, Full Professor, Department of Hepatology, CHU Avicenne-APHP, 125 Rue de Stalingrad, Bobigny 93000, France. naultjc@gmail.com |
Key Words |
Hepatocellular carcinoma; Transarterial chemoembolization; Bland embolization; Sarcopenia; Skeletal muscle index |
Core Tip |
This work evaluates the predictive value of sarcopenia on tumor response and survival outcomes in hepatocellular carcinoma patients treated by transarterial chemoembolization or transarterial embolization. In this article, sarcopenia at imaging was observed in 57.7% of patients. It was associated with a higher rate of progressive disease and a decreased overall survival after adjustment with usual risk factors of death. Sarcopenia is an easy-to-assess radiological biomarker of poor prognosis that should be measured in order to assess prognosis and test a targeted intervention mixing nutritional support and physical activity. |
Publish Date |
2022-09-23 10:13 |
Citation |
Roth G, Teyssier Y, Benhamou M, Abousalihac M, Caruso S, Sengel C, Seror O, Ghelfi J, Seigneurin A, Ganne-Carrie N, Gigante E, Blaise L, Sutter O, Decaens T, Nault JC. Impact of sarcopenia on tumor response and survival outcomes in patients with hepatocellular carcinoma treated by trans-arterial (chemo)-embolization. World J Gastroenterol 2022; 28(36): 5324-5337 |
URL |
https://www.wjgnet.com/1007-9327/full/v28/i36/5324.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v28.i36.5324 |