| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
High incidence combination of multiple primary malignant tumors of the digestive system
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xiao-Bo Yang, Long-Hao Zhang, Jing-Nan Xue, Yun-Chao Wang, Xu Yang, Nan Zhang, Dan Liu, Yan-Yu Wang, Zi-Yu Xun, Yi-Ran Li, Hui-Shan Sun, Li-Jin Zhao and Hai-Tao Zhao |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| CAMS Innovation Fund for Medical Sciences |
2021-I2M-1-061, 2021-1-I2M-003 |
| CSCO-hengrui Cancer Research Fund |
Y-HR2019-0239 |
| CSCO-MSD Cancer Research Fund |
Y-MSDZD2021-0213 |
| National Ten-thousand Talent Program |
|
|
| Corresponding Author |
Hai-Tao Zhao, PhD, Professor, Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 1 Shuaifuyuan, Dongcheng District, Beijing 100006, China. zhaoht@pumch.cn |
| Key Words |
Multiple primary malignant tumors; Colon cancer; Rectal cancer; Metachronous carcinoma; High incidence combinations; First primary carcinoma |
| Core Tip |
This is a retrospective study to explore the high incidence combination of multiple primary malignant tumors (MPMTs). Among the 1902 patients with MPMTs confirmed by pathology, after excluding the effect of male-female specific malignancies, it was found that digestive system malignancies were very common as the first primary cancer. Therefore, the common combination of second primary cancers should be followed up at the limit of 6 mo after the detection of digestive system malignancies. Without excluding the influence of male-female specific malignancies, it was found that the combination of breast cancer and nonuterine cancer was the most common in metachronous multiple primary malignancies, and the combination of colon cancer and rectal cancer was the most common in synchronous multiple primary malignancies. |
| Publish Date |
2022-11-04 05:24 |
| Citation |
Yang XB, Zhang LH, Xue JN, Wang YC, Yang X, Zhang N, Liu D, Wang YY, Xun ZY, Li YR, Sun HS, Zhao LJ, Zhao HT. High incidence combination of multiple primary malignant tumors of the digestive system. World J Gastroenterol 2022; 28(41): 5982-5992 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i41/5982.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i41.5982 |
