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Articles Published Processes
12/27/2022 10:06:45 AM | Browse: 150 | Download: 387
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Received |
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2022-09-25 11:52 |
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Peer-Review Started |
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2022-09-25 11:55 |
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To Make the First Decision |
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Return for Revision |
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2022-10-30 16:50 |
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Revised |
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2022-11-01 22:09 |
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Second Decision |
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2022-11-25 03:06 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2022-11-26 15:23 |
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Articles in Press |
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2022-11-26 15:23 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-12-02 21:51 |
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Typeset the Manuscript |
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2022-12-20 14:43 |
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Publish the Manuscript Online |
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2022-12-27 10:06 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Minireviews |
| Article Title |
Current and future perspectives on acute-on-chronic liver failure: Challenges of transplantation, machine perfusion and beyond
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Bianca Della Guardia, Amanda P C S Boteon, Celso E L Matielo, Guilherme Felga and Yuri L Boteon |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Yuri L Boteon, MD, PhD, Doctor, Professor, Surgeon, Liver Unit, Hospital Israelita Albert Einstein, Transplant Centre, Hospital Israelita Albert Einstein, 2nd floor, building A1, Office 200B, 627/701 Albert Einstein Avenue, São Paulo 05652-900, Brazil. yuri.boteon@einstein.br |
| Key Words |
Acute-on-chronic liver failure; Liver cirrhosis; Liver transplantation; Machine perfusion; Hypothermic oxygenated machine perfusion |
| Core Tip |
Acute-on-chronic liver failure (ACLF) is characterised by high short-term mortality. Although new clinical specific therapies have been researched, more studies are necessary to assess safety and efficacy. Conversely, earlier transplantation is proven to be effective for selected patients. Therefore, future ACLF management strategies must consider measures to improve access to liver transplantation. Discussions about donor organ allocation and recipient prioritisation are necessary because there is evidence suggesting the current model may not portray the waitlist mortality of these patients. In this scenario, machine perfusion of the liver may prove to be a safe tool to improve the donor organ pool. |
| Publish Date |
2022-12-27 10:06 |
| Citation |
Della Guardia B, Boteon APCS, Matielo CEL, Felga G, Boteon YL. Current and future perspectives on acute-on-chronic liver failure: Challenges of transplantation, machine perfusion and beyond. World J Gastroenterol 2022; 28(48): 6922-6934 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i48/6922.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i48.6922 |
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