Publication Name	World Journal of Clinical Cases
Manuscript ID	81413
Country	China

Received	2024-01-11 13:08
Peer-Review Started	2024-01-11 13:08
To Make the First Decision
Return for Revision	2024-02-26 14:35
Revised	2024-03-03 07:06
Second Decision	2024-04-01 01:39
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-04-01 08:16
Articles in Press	2024-04-01 08:16
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-04-15 01:54
Publish the Manuscript Online	2024-04-25 08:14

ISSN	2307-8960 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Clinical Trials Study
Article Title	Yiwei Xiaoyu Granules for treatment of chronic atrophic gastritis with deficiency syndrome of the spleen and stomach
Manuscript Source	Unsolicited Manuscript
All Author List	Wan-Qun Chen, Qing-Feng Fan, Yuan-Jun He, Fei Li, Xin Wu, Yan-Ping Li and Xiao-Jun Yang
ORCID	Author(s) ORCID Number Wan-Qun Chen http://orcid.org/0000-0002-1126-2968 Yan-Ping Li http://orcid.org/0000-0002-4983-014X Xiao-Jun Yang http://orcid.org/0000-0003-3768-8649
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81904175 Chongqing Health Planning Commission Project ZY201802063 Chongqing Health Planning Commission Project 2019ZY013111 Chongqing Technology Innovation and Application development special key project CSTB2022TIAD-KPX0187 Chongqing Health Planning Commission Project 2022QNXM061
Corresponding Author	Xiao-Jun Yang, PhD, Doctor, Department of Gastroenterology, Chongqing Hospital of Traditional Chinese Medicine, No. 6 Panxi Seven Branch Road, Jiangbei District, Chongqing 400000, China. yxj20220606@163.com
Key Words	Chronic atrophic gastritis; Yiwei Xiaoyu granules; Randomized clinical trial; Weifuchun tablet; Traditional Chinese medicine; Helicobacter pylori
Core Tip	Despite the successful eradication of Helicobacter pylori (H. pylori), which has been shown to reduce the risk of gastric cancer (GC), patients with chronic atrophic gastritis (CAG) still remain susceptible to disease progression leading to GC. Our findings suggest that treatment with Yiwei Xiaoyu granules for CAG patients without H. pylori improved the stage of Operative Link on Gastric Intestinal Metaplasia Assessment, provided better clinical symptoms relief and better improvement in serum gastric function levels compared to Weifuchun tablet. However, the total sample size of this study is limited and prolong follow-up hasn’t been carried out.
Publish Date	2024-04-25 08:14
Citation	Chen WQ, Fan QF, He YJ, Li F, Wu X, Li YP, Yang XJ. Yiwei Xiaoyu Granules for treatment of chronic atrophic gastritis with deficiency syndrome of the spleen and stomach. World J Clin Cases 2024; 12(13): 2201-2209
URL	https://www.wjgnet.com/2307-8960/full/v12/i13/2201.htm
DOI	https://dx.doi.org/10.12998/wjcc.v12.i13.2201

Full Article (PDF)	WJCC-12-2201-with-cover.pdf
CONSORT 2010 Statement	81413-CONSORT 2010 statement.pdf
Manuscript File	81413_Auto_Edited-LJH-YJP.docx
Answering Reviewers	81413-Answering reviewers.pdf
Audio Core Tip	81413-Audio core tip.m4a
Biostatistics Review Certificate	81413-Biostatistics statement.pdf
Clinical Trial Registration Statement	81413-Clinical Trial Registration Statement.pdf
Conflict-of-Interest Disclosure Form	81413-Conflict-of-interest statement.pdf
Copyright License Agreement	81413-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	81413-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s)	81413-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	81413-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	81413-Language certificate.pdf
Peer-review Report	81413-Peer-review(s).pdf
Scientific Misconduct Check	81413-Bing-Liu JH-2.png
Scientific Misconduct Check	81413-CrossCheck.png
Scientific Editor Work List	81413-Scientific editor work list.pdf