| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Critical Care Medicine |
| Manuscript Type |
Minireviews |
| Article Title |
Evolving paradigm of thrombolysis in pulmonary embolism: Comprehensive review of clinical manifestations, indications, recent advances and guideline
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Rohan Kumar Ochani, Rafi Aibani, Hafsa Nazir Jatoi, Masroor Anwar, Syed Anjum Khan, Iqbal Ratnani and Salim Surani |
| ORCID |
|
| Funding Agency and Grant Number |
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| Corresponding Author |
Salim Surani, FCCP, MD, MS, Professor, Department of Medicine, Texas A&M University, Administration Building, 400 Bizzell St, College Station, TX 77843, United States. srsurani@hotmail.com |
| Key Words |
Pulmonary Embolism; Thrombolytics; Systemic; Catheter-directed; Pulmonary Embolism Reaction Team; Guidelines |
| Core Tip |
There are now many treatments to treat acute pulmonary embolism (PE). Patients are divided into low, moderate, and high-risk PE groups to identify those needing more advanced treatment. Unless contraindicated, systemic thrombolysis is advised for high-risk pulmonary embolism. Other than systemic thrombolysis, a number of treatment options for PE are being investigated, such as catheter-directed thrombolysis, extracorporeal membrane oxygenation, direct aspiration, or fragmentation with aspiration. Choosing the appropriate course of treatment for a certain patient may be challenging due to the plethora of therapeutic choices that are continually evolving and the paucity of randomized controlled trials. Therefore, the Pulmonary Embolism Reaction Team, is a multidisciplinary, rapid response team has been developed and is employed by various institutions to customize therapeutic options according to the need of the patient to address the ever-evolving therapeutic care. |
| Publish Date |
2023-03-07 08:12 |
| Citation |
Ochani RK, Aibani R, Jatoi HN, Anwar M, Khan SA, Ratnani I, Surani S. Evolving paradigm of thrombolysis in pulmonary embolism: Comprehensive review of clinical manifestations, indications, recent advances and guideline. World J Clin Cases 2023; 11(8): 1702-1711 |
| URL |
https://www.wjgnet.com/2307-8960/full/v11/i8/1702.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v11.i8.1702 |
