Publication Name	World Journal of Gastroenterology
Manuscript ID	8243
Country	Italy

Received	2013-12-22 13:14
Peer-Review Started	2013-12-23 09:58
To Make the First Decision	2014-01-15 19:31
Return for Revision	2014-03-26 14:07
Revised
Second Decision	2014-04-16 11:32
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-04-16 12:03
Articles in Press	2014-05-23 10:48
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-04-24 22:23
Typeset the Manuscript	2014-07-12 14:49
Publish the Manuscript Online	2014-07-26 13:36

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Field of Vision
Article Title	Could metabolic syndrome lead to hepatocarcinoma via non-alcoholic fatty liver disease?
Manuscript Source	Invited Manuscript
All Author List	Antonella Scalera and Giovanni Tarantino
Funding Agency and Grant Number
Corresponding Author	Giovanni Tarantino, MD, Department of Clinical Medicine and Surgery, Federico II University Medical School of Naples, Via Sergio Pansini 5, 80131 Naples, Italy. tarantin@unina.it
Key Words	Hepatocarcinoma; Non-alcoholic fatty liver disease; Insulin growth factor; Peroxisome proliferator-activated receptor γ; Adipokines
Core Tip	Obesity, metabolic syndrome and type 2 diabetes mellitus are strictly related and are key pathogenetic factors in non-alcoholic fatty liver disease, one of the most frequent liver diseases worldwide. It is necessary to stress that one of the most important consequences of the “metabolic epidemics” is the probable rise in the incidence of cancers, particularly hepatocarcinoma. Thus, to improve survival, efforts to achieve a “healthier diet” should be promoted by physicians and politicians, even though no changes in genes have been observed in the postprandial state induced after the acute effect of specific diets in patients exhibiting non-alcoholic fatty liver disease and insulin resistance.
Publish Date	2014-07-26 13:36
Citation	Scalera A, Tarantino G. Could metabolic syndrome lead to hepatocarcinoma via non-alcoholic fatty liver disease? World J Gastroenterol 2014; 20(28): 9217-9228
URL	http://www.wjgnet.com/1007-9327/full/v20/i28/9217.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i28.9217

Full Article (PDF)	WJG-20-9217.pdf
Full Article (Word)	WJG-20-9217.doc
Manuscript File	8243-Review.doc
Answering Reviewers	8243-Answering reviewers.pdf
Copyright License Agreement	8243-Copyright assignment.pdf
Peer-review Report	8243-Peer review.pdf
Scientific Editor Work List	8243-Scientific editor work list.doc