Publication Name	World Journal of Gastroenterology
Manuscript ID	86186
Country	China

Received	2023-06-10 02:08
Peer-Review Started	2023-06-10 02:10
To Make the First Decision
Return for Revision	2023-07-10 04:21
Revised	2023-07-19 08:20
Second Decision	2023-08-31 02:46
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2023-08-31 17:43
Articles in Press	2023-08-31 17:43
Publication Fee Transferred
Edit the Manuscript by Language Editor	2023-08-23 22:31
Typeset the Manuscript	2023-09-08 08:40
Publish the Manuscript Online	2023-09-14 14:58

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Developments and challenges in neoadjuvant therapy for locally advanced pancreatic cancer
Manuscript Source	Invited Manuscript
All Author List	Bo Zhou, Shi-Ran Zhang, Geng Chen and Ping Chen
ORCID	Author(s) ORCID Number Bo Zhou http://orcid.org/0000-0001-8376-3182 Geng Chen http://orcid.org/0000-0002-1642-7098 Ping Chen http://orcid.org/0000-0001-6575-8582
Funding Agency and Grant Number
Corresponding Author	Ping Chen, MD, PhD, Professor, Surgeon, Department of Hepatobiliary Surgery, Daping Hospital, Army Medical University, No. 10 Changjiang Branch Road, Yuzhong District, Chongqing 400042, China. chenpingsyd@126.com
Key Words	Neoadjuvant therapy; Pancreatic ductal adenocarcinoma; Locally advanced pancreatic cancer; Chemoradiotherapy; Immunotherapy; Vaccine therapy
Core Tip	In recent years, neoadjuvant therapy (NAT) has emerged as a promising treatment option for many cancer types, including locally advanced pancreatic ductal adenocarcinoma, with the potential to improve patient outcomes. To analyze the role of NAT in the setting of locally advanced pancreatic ductal adenocarcinoma over the past decade, a systematic literature search was conducted using PubMed and Web of Science. Despite the potential benefits of NAT, there are still challenges that need to be addressed. Additionally, there is a need for better patient selection criteria to identify those who are most likely to benefit from this approach.
Publish Date	2023-09-14 14:58
Citation	Zhou B, Zhang SR, Chen G, Chen P. Developments and challenges in neoadjuvant therapy for locally advanced pancreatic cancer. World J Gastroenterol 2023; 29(35): 5094-5103
URL	https://www.wjgnet.com/1007-9327/full/v29/i35/5094.htm
DOI	https://dx.doi.org/10.3748/wjg.v29.i35.5094

Full Article (PDF)	WJG-29-5094-with-cover.pdf
Full Article (Word)	WJG-29-5094.docx
Manuscript File	86186_Auto_Edited-LM.docx
Answering Reviewers	86186-Answering reviewers.pdf
Audio Core Tip	86186-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	86186-Conflict-of-interest statement.pdf
Copyright License Agreement	86186-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	86186-Language certificate.pdf
Peer-review Report	86186-Peer-review(s).pdf
Scientific Misconduct Check	86186-Bing-Yan JP-2.png
Scientific Editor Work List	86186-Scientific editor work list.pdf