Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	87319
Country	China

Received	2023-08-04 07:31
Peer-Review Started	2023-08-04 07:33
To Make the First Decision
Return for Revision	2023-10-23 08:29
Revised	2023-11-20 04:38
Second Decision	2023-12-12 03:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2023-12-12 08:52
Articles in Press	2023-12-12 08:52
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-01-03 07:36
Publish the Manuscript Online	2024-01-11 06:17

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Prognostic significance and relationship of SMAD3 phospho-isoforms and VEGFR-1 in gastric cancer: A clinicopathological study
Manuscript Source	Unsolicited Manuscript
All Author List	Shi-Lin Lv, Pei Guo, Jun-Rong Zou, Ren-Sheng Chen, Ling-Yu Luo and De-Qiang Huang
ORCID	Author(s) ORCID Number Ling-Yu Luo http://orcid.org/0000-0002-1090-0198 De-Qiang Huang http://orcid.org/0000-0003-3467-5359
Funding Agency and Grant Number	Funding Agency Grant Number National Nature Science Foundation of China 82060450 National Nature Science Foundation of China 82360517 National Nature Science Foundation of China 81460374 National Nature Science Foundation of China 31460304 Nature Science Foundation of Jiangxi Province of China 20232BAB206086 Nature Science Foundation of Jiangxi Province of China 20192BAB205072 Nature Science Foundation of Jiangxi Province of China 20203BBGL73206 Nature Science Foundation of Jiangxi Province of China 2017BCB23086 Nature Science Foundation of Jiangxi Province of China 2017BAB205062 Nature Science Foundation of Jiangxi Province of China 20181BAB205050
Corresponding Author	De-Qiang Huang, MD, N/A, Hospital of Gastroenterology, Institute of Digestive Diseases, The First Affiliated Hospital of Nanchang University, No. 17 Yongwaizen Street, Nanchang 330006, Jiangxi Province, China. hdq0515@ncu.edu.cn
Key Words	Gastric cancer; pSMAD3L (S204); pSMAD3C (S423/425); Survival; Transforming growth factor-β1; VEGFR-1
Core Tip	This study investigated the prognostic value and relationship between SMAD3 phospho-isoforms and VEGFR-1 in gastric cancer. The results showed that high expression of both pSMAD3L(S204) and VEGFR-1 was associated with poor overall survival in gastric cancer patients. Co-upregulation of pSMAD3L(S204) and VEGFR-1 can serve as a predictive marker for poor gastric cancer prognosis.
Publish Date	2024-01-11 06:17
Citation	Lv SL, Guo P, Zou JR, Chen RS, Luo LY, Huang DQ. Prognostic significance and relationship of SMAD3 phospho-isoforms and VEGFR-1 in gastric cancer: A clinicopathological study. World J Gastrointest Oncol 2024; 16(1): 118-132
URL	https://www.wjgnet.com/1948-5204/full/v16/i1/118.htm
DOI	https://dx.doi.org/10.4251/wjgo.v16.i1.118

Full Article (PDF)	WJGO-16-118-with-cover.pdf
Full Article (Word)	WJGO-16-118.docx
STROBE Statement	87319-STROBE statement.pdf
Manuscript File	87319_Auto_Edited-YJP.doc
Answering Reviewers	87319-Answering reviewers.pdf
Audio Core Tip	87319-Audio core tip.aac
Biostatistics Review Certificate	87319-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	87319-Conflict-of-interest statement.pdf
Copyright License Agreement	87319-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	87319-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s)	87319-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	87319-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	87319-Language certificate.pdf
Peer-review Report	87319-Peer-review(s).pdf
Scientific Misconduct Check	87319-Bing-Lin C-2.png
Scientific Editor Work List	87319-Scientific editor work list.pdf