Publication Name	World Journal of Hepatology
Manuscript ID	8873
Country	India

Received	2014-01-11 12:02
Peer-Review Started	2014-01-11 16:55
To Make the First Decision	2014-01-23 17:17
Return for Revision	2014-02-09 21:18
Revised	2014-03-01 14:56
Second Decision	2014-05-19 09:09
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-05-19 09:25
Articles in Press	2014-05-23 12:24
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-05-26 03:54
Typeset the Manuscript	2014-07-01 12:14
Publish the Manuscript Online	2014-07-04 18:01

ISSN	1948-5182 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Case Control Study
Article Title	Pooled genetic analysis in ultrasound measured non-alcoholic fatty liver disease in Indian subjects: a pilot study
Manuscript Source	Unsolicited Manuscript
All Author List	Vishnubhotla Venkata Ravi Kanth, Mitnala Sasikala, Padaki Nagaraja Rao, Urmila Steffie Avanthi, Kalashikam Rajender Rao and Duvvuru Nageshwar Reddy
Funding Agency and Grant Number
Corresponding Author	Padaki Nagaraja Rao, Chief of Hepatology and Nutrition, Asian Institute of Gastroenterology, 6-3-661, Somajiguda, Hyderabad 500 082, India. npadaki@yahoo.com
Key Words	Non-alcoholic fatty liver disease; Genome wide association studies; Genetic association; Hepatic steatosis; Genotyping; Single nucleotide polymorphisms; Susceptibility
Core Tip	Non-alcoholic fatty liver disease (NAFLD) describes a range of conditions caused by build-up of fat within liver cells in the absence of alcohol consumption. Although obesity, diabetes, age, hypertension and hypertriglyceridemia contribute to the disease, genetics also has an important role to play. Furthermore, in 26-35% of patients, the genetic component is believed to contribute to NAFLD. By identifying significant single nucleotide polymorphisms from genome wide association studies reported from different ethnic populations for NAFLD and performing a pooled genetic association study, this study has identified important genetic risks that could help in identifying individuals with susceptibility at an early stage, thus aiding in better management of the disease.
Publish Date	2014-07-04 18:01
Citation	Ravi Kanth VV, Sasikala M, Rao PN, Steffie Avanthi U, Rajender Rao KR, Nageshwar Reddy D. Pooled genetic analysis in ultrasound measured non-alcoholic fatty liver disease in Indian subjects: A pilot study. World J Hepatol 2014; 6(6): 435-442
URL	http://www.wjgnet.com/1948-5182/full/v6/i6/435.htm
DOI	http://dx.doi.org/10.4254/wjh.v6.i6.435

Full Article (PDF)	WJH-6-435.pdf
Full Article (Word)	WJH-6-435.doc
Manuscript File	8873-Review.docx
Answering Reviewers	8873-Answering reviewers.pdf
Biostatistics Review Certificate	Biostatistician_Review_Report_20140109195638.docx
Copyright License Agreement	8873-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	Ethics_Committee_20140109195619.docx
Peer-review Report	8873-Peer review(s).pdf
Scientific Editor Work List	8873-Scientific editor work list.pdf