ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Observational Study |
Article Title |
Preoperative albumin-bilirubin score and liver resection percentage determine postoperative liver regeneration after partial hepatectomy
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Manuscript Source |
Invited Manuscript |
All Author List |
Kazuhiro Takahashi, Masahiko Gosho, Yoshihiro Miyazaki, Hiromitsu Nakahashi, Osamu Shimomura, Kinji Furuya, Manami Doi, Yohei Owada, Koichi Ogawa, Yusuke Ohara, Yoshimasa Akashi, Tsuyoshi Enomoto, Shinji Hashimoto and Tatsuya Oda |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Kazuhiro Takahashi, FACS, MD, PhD, Assistant Professor, Surgeon, Department of Gastrointestinal and Hepatobiliary-Pancreatic Surgery, University of Tsukuba, Tennodai 1-1-1, Tsukuba 3058-575, Ibaraki, Japan. kazu1123@md.tsukuba.ac.jp |
Key Words |
Liver regeneration; Albumin-bilirubin score; Liver resection percentage; Partial hepatectomy; Human; Regeneration index |
Core Tip |
Insights into posthepatectomy liver regeneration in humans are limited. We quantified liver volumes using the latest volumetric software and investigated perioperative factors that affect posthepatectomy liver regeneration. It was revealed that liver regeneration continues after 3 months of hepatectomy with more than one-fourth of the liver resection and decline in preoperative liver function, reflected by the albumin-bilirubin (ALBI) score, is associated with decreased regeneration. Furthermore, restoring to the original volume depended on the combination of the preoperative ALBI score and liver resection percentage. With this knowledge, surgeons can select an appropriate hepatectomy type with rehepatectomy in mind after intrahepatic recurrence. |
Publish Date |
2024-04-12 16:45 |
Citation |
Takahashi K, Gosho M, Miyazaki Y, Nakahashi H, Shimomura O, Furuya K, Doi M, Owada Y, Ogawa K, Ohara Y, Akashi Y, Enomoto T, Hashimoto S, Oda T. Preoperative albumin-bilirubin score and liver resection percentage determine postoperative liver regeneration after partial hepatectomy. World J Gastroenterol 2024; 30(14): 2006-2017 |
URL |
https://www.wjgnet.com/1007-9327/full/v30/i14/2006.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v30.i14.2006 |