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Articles Published Processes
9/15/2014 8:55:00 PM | Browse: 1283 | Download: 1198
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Received |
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2013-02-28 16:57 |
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Peer-Review Started |
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2013-03-01 11:57 |
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To Make the First Decision |
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2013-03-18 15:40 |
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Return for Revision |
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2013-03-20 08:33 |
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Revised |
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2013-04-18 07:39 |
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Second Decision |
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2013-05-09 13:02 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2013-05-10 10:51 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-06-25 19:26 |
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Publish the Manuscript Online |
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2013-07-06 17:46 |
Category |
Research & Experimental Medicine |
Manuscript Type |
Review |
Article Title |
Why interleukin-10 supplementation does not work in Crohn's disease patients
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Manuscript Source |
Invited Manuscript |
All Author List |
Gareth J Marlow, Dominique van Gent and Lynnette R Ferguson |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Ministry of Business, Innovation and Employment |
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Dutch Digestive Foundation |
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Corresponding Author |
Lynnette R Ferguson, Professor, Discipline of Nutrition, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. l.ferguson@auckland.ac.nz
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Key Words |
Inflammatory bowel disease; Crohn's disease; Interleukin-10; Recombinant human interleukin-10 |
Core Tip |
Inflammatory bowel disease (IBD) is a chronic condition with no known cure. This review addresses the current available treatments for IBD before discussing a potential new treatment strategy using the immunoregulatory cytokine interleukin-10 (IL-10). To date clinical trial results have been disappointing. We highlight the limitations of current IL-10 supplementation treatment and suggest how, with changes to IL-10 delivery and the correct choice of patient, IL-10 supplementation could become a viable treatment option.
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Publish Date |
2013-07-06 17:46 |
Citation |
Marlow GJ, van Gent D, Ferguson LR. Why interleukin-10 supplementation does not work in Crohn’s disease patients. World J Gastroenterol 2013; 19(25): 3931-3941 |
URL |
http://www.wjgnet.com/1007-9327/full/v19/i25/3931.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v19.i25.3931 |
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