| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Prediction of the severity of acute pancreatitis on admission by urinary trypsinogen activation peptide: A meta-analysis
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Wei Huang, Kiran Altaf, Tao Jin, Jun-Jie Xiong, Li Wen, Muhammad A Javed, Marianne Johnstone, Ping Xue, Christopher M Halloran and Qing Xia |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Technology Supported Program of Sichuan Province, China |
2011SZ0291 |
| National Natural Science Foundation of China |
81072910 |
| National Institute for Health Research, United Kingdom |
|
|
| Corresponding Author |
Ping Xue, MD, PhD, Sichuan Provincial Pancreatitis Center, Department of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University, Guoxue Rd 37, Chengdu 610041, Sichuan Province, China. sppc.wch.scu@gmail.com
|
| Key Words |
Acute pancreatitis; Urinary trypsinogen activation peptide; C-reactive protein; Acute Physiology and Chronic Health Evaluation Ⅱ score; Meta-analysis |
| Core Tip |
Currently, the assessment of acute pancreatitis severity on admission remains a challenge to clinicians. A single, rapid biochemical marker is the preferred choice than clinical and computed tomography scoring systems. In this study, the value of urinary trypsinogen activation peptide (uTAP), on admission, in predicting severity of acute pancreatitis was assessed. It was found that the ability of uTAP to predict severity of acute pancreatitis on admission was comparable to C-reactive protein (at 48 h) and was potentially better than the Acute Physiology and Chronic Health Evaluation Ⅱ score (at 48 h), the most frequently used biochemical marker and clinical scoring system in acute pancreatitis, respectively. |
| Publish Date |
2013-07-29 11:18 |
| Citation |
Huang W, Altaf K, Jin T, Xiong JJ, Wen L, Javed MA, Johnstone M, Xue P, Halloran CM, Xia Q. Prediction of the severity of acute pancreatitis on admission by urinary trypsinogen activation peptide: A meta-analysis. World J Gastroenterol 2013; 19(28): 4607-4615 |
| URL |
http://www.wjgnet.com/1007-9327/full/v19/i28/4607.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v19.i28.4607 |
