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Publication Name World Journal of Cardiology
Manuscript ID 3330
Country/Territory Italy
Received
2013-04-23 09:47
Peer-Review Started
2013-04-23 19:43
To Make the First Decision
2013-05-14 18:54
Return for Revision
2013-05-18 15:57
Revised
2013-06-05 05:11
Second Decision
2013-06-18 14:55
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-06-19 01:14
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-07-11 18:58
Publish the Manuscript Online
2013-08-02 14:08
ISSN 1949-8462 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pharmacology & Pharmacy
Manuscript Type Case Report
Article Title Berberine behind the thriller of marked symptomatic bradycardia
Manuscript Source Invited Manuscript
All Author List Margherita Cannillo, Simone Frea, Cristina Fornengo, Elisabetta Toso, Giancarlo Mercurio, Stefania Battista and Fiorenzo Gaita
Funding Agency and Grant Number
Corresponding Author Margherita Cannillo, MD, Division of Cardiology, Cardiovascular Department, AOU S. Giovanni Battista di Torino and University of Torino, Corso Bramante 88, 10100 Turino, Italy. margheritacannillo@gmail.com.
Key Words Berberine; Bradyarrhythmia; Side effect; Hypervagotonia; Hypercholesterolaemia; Electrocardiogram
Core Tip Berberine is widely used in traditional Chinese medicine for the treatment of congestive heart failure, hypertension, diabetes, and dyslipidaemia. We report a case of marked symptomatic sinus bradycardia with competitive junctional rhythm caused by berberine, showing that berberine, due to its antiarrhythmic properties, can cause the onset of bradyarrhythmia. In this case report, we focus on the possible side effects of so-called natural medicine based on holistic, home, and herbal remedies, which is considered to be safe only because the treatment is natural. However, under certain conditions, natural medicine can lead to potential health risks in patients.
Publish Date 2013-08-02 14:08
Citation Cannillo M, Frea S, Fornengo C, Toso E, Mercurio G, Battista S, Gaita F. Berberine behind the thriller of marked symptomatic bradycardia. World J Cardiol 2013; 5(7): 261-264
URL http://www.wjgnet.com/1949-8462/full/v5/i7/261.htm
DOI http://dx.doi.org/10.4330/wjc.v5.i7.261
Full Article (PDF) WJC-5-261.pdf
Manuscript File 3330-Review.doc
Answering Reviewers 3330-Answering reviewers.pdf
Copyright License Agreement 3330-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 3330-Language certificate.pdf
Peer-review Report 3330-Peer review(s).pdf
Scientific Editor Work List 3330-Scientific editor work list.doc