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Publication Name World Journal of Gastroenterology
Manuscript ID 3698
Country/Territory Saudi Arabia
Received
2013-05-16 08:05
Peer-Review Started
2013-05-16 14:48
To Make the First Decision
2013-07-19 08:27
Return for Revision
2013-07-25 16:48
Revised
2013-08-06 17:52
Second Decision
2013-08-13 11:47
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-08-13 13:35
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-10-26 10:00
Publish the Manuscript Online
2013-11-08 14:06
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research & Experimental
Manuscript Type Review
Article Title Concepts of oxidative stress and antioxidant defense in Crohn's disease
Manuscript Source Invited Manuscript
All Author List Mohammed A Alzoghaibi
Funding Agency and Grant Number
Corresponding Author Mohammed A Alzoghaibi, PhD, Department of Physiology, College of Medicine, King Saud University, Amr Ibn Al As, PO Box 2925, Riyadh 11461, Saudi Arabia. zzoghaibi@gmail.com
Key Words Crohn's disease; Reactive oxygen species; Antioxidant enzymes; Lipid peroxide
Core Tip Crohn's disease is associated with an imbalance, comprising increased reactive oxygen species (ROS) and decreased net antioxidant activity. A deficiency in antioxidant molecules could lead to increased levels of lipid peroxides or ROS, which could act locally or be secreted into the circulation to produce different systemic effects in the patient. Future research should address the question of whether ROS are involved in increasing the production of the different extracellular proteins by enhancing the transcriptions of certain genes using specific transcription factors.
Publish Date 2013-11-08 14:06
Citation Alzoghaibi MA. Concepts of oxidative stress and antioxidant defense in Crohn’s disease. World J Gastroenterol 2013; 19(39): 6540-6547
URL http://www.wjgnet.com/1007-9327/full/v19/i39/6540.htm
DOI http://dx.doi.org/10.3748/wjg.v19.i39.6540
Full Article (PDF) WJG-19-6540.pdf
Manuscript File 3698-Review.doc
Answering Reviewers 3698-Answering reviewers.pdf
Copyright License Agreement 3698-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 3698-Language certificate.pdf
Peer-review Report 3698-Peer reviews.pdf
Scientific Editor Work List 3698-Scientific editor work list.doc