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Articles Published Processes
9/12/2014 8:40:00 PM | Browse: 1108 | Download: 1133
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Received |
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2013-07-10 08:48 |
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Peer-Review Started |
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2013-07-10 09:25 |
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To Make the First Decision |
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2013-08-08 11:25 |
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Return for Revision |
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2013-08-12 21:00 |
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Revised |
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2013-08-19 15:11 |
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Second Decision |
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2013-09-05 11:26 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2013-09-05 13:02 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2013-09-12 16:15 |
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Typeset the Manuscript |
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2013-10-17 15:36 |
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Publish the Manuscript Online |
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2013-11-08 14:06 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Topic Highlights |
Article Title |
Risk prediction of hepatitis B virus-related hepatocellular carcinoma in the era of antiviral therapy
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Manuscript Source |
Invited Manuscript |
All Author List |
Grace Lai-Hung Wong and Vincent Wai-Sun Wong |
Funding Agency and Grant Number |
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Corresponding Author |
Vincent WS Wong, MD, Institute of Digestive Disease and Department of Medicine and Therapeutics, The Chinese University of Hong Kong, 9/F Prince of Wales Hospital, 30-32 Ngan Shing Street, Shatin, Hong Kong, China. wongv@cuhk.edu.hk |
Key Words |
Antiviral therapy; Cirrhosis; Hepatitis B virus DNA; Hepatocellular carcinoma; Risk prediction score; Transient elastography |
Core Tip |
CU-hepatocellular carcinoma (HCC), GAG-HCC and REACH-B scores accurately predict subsequent HCC development in both treatment-na?ve patients with chronic hepatitis B and those receiving antiviral therapy. At the recommended cutoff values, baseline CU-HCC and REACH-B scores had high sensitivity, while the GAG-HCC score had high specificity in predicting HCC. Patients persistently in the low-risk category have the lowest risk of HCC; those “downgraded” in risk category have significantly lower, but a small risk of HCC compared to those in the high-risk category. Patients in the high-risk category either at baseline or after treatment should undergo HCC surveillance. |
Publish Date |
2013-11-08 14:06 |
Citation |
Wong GLH, Wong VWS. Risk prediction of hepatitis B virus-related hepatocellular carcinoma in the era of antiviral therapy. World J Gastroenterol 2013; 19(39): 6515-6522 |
URL |
http://www.wjgnet.com/1007-9327/full/v19/i39/6515.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v19.i39.6515 |
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