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9/12/2014 8:40:00 PM | Browse: 1108 | Download: 1133
Publication Name World Journal of Gastroenterology
Manuscript ID 4588
Country/Territory China
Received
2013-07-10 08:48
Peer-Review Started
2013-07-10 09:25
To Make the First Decision
2013-08-08 11:25
Return for Revision
2013-08-12 21:00
Revised
2013-08-19 15:11
Second Decision
2013-09-05 11:26
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-09-05 13:02
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
2013-09-12 16:15
Typeset the Manuscript
2013-10-17 15:36
Publish the Manuscript Online
2013-11-08 14:06
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Topic Highlights
Article Title Risk prediction of hepatitis B virus-related hepatocellular carcinoma in the era of antiviral therapy
Manuscript Source Invited Manuscript
All Author List Grace Lai-Hung Wong and Vincent Wai-Sun Wong
Funding Agency and Grant Number
Corresponding Author Vincent WS Wong, MD, Institute of Digestive Disease and Department of Medicine and Therapeutics, The Chinese University of Hong Kong, 9/F Prince of Wales Hospital, 30-32 Ngan Shing Street, Shatin, Hong Kong, China. wongv@cuhk.edu.hk
Key Words Antiviral therapy; Cirrhosis; Hepatitis B virus DNA; Hepatocellular carcinoma; Risk prediction score; Transient elastography
Core Tip CU-hepatocellular carcinoma (HCC), GAG-HCC and REACH-B scores accurately predict subsequent HCC development in both treatment-na?ve patients with chronic hepatitis B and those receiving antiviral therapy. At the recommended cutoff values, baseline CU-HCC and REACH-B scores had high sensitivity, while the GAG-HCC score had high specificity in predicting HCC. Patients persistently in the low-risk category have the lowest risk of HCC; those “downgraded” in risk category have significantly lower, but a small risk of HCC compared to those in the high-risk category. Patients in the high-risk category either at baseline or after treatment should undergo HCC surveillance.
Publish Date 2013-11-08 14:06
Citation Wong GLH, Wong VWS. Risk prediction of hepatitis B virus-related hepatocellular carcinoma in the era of antiviral therapy. World J Gastroenterol 2013; 19(39): 6515-6522
URL http://www.wjgnet.com/1007-9327/full/v19/i39/6515.htm
DOI http://dx.doi.org/10.3748/wjg.v19.i39.6515
Full Article (PDF) WJG-19-6515.pdf
Manuscript File 4588-Review.docx
Answering Reviewers 4588-Answering reviewers.pdf
Copyright License Agreement 4588-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 4588-Language certificate.pdf
Peer-review Report 4588-Peer reviews.pdf
Scientific Editor Work List 4588-Scientific editor work list.doc