Publication Name	World Journal of Gastroenterology
Manuscript ID	101915
Country	Germany

Category	Gastroenterology & Hepatology
Manuscript Type	Prospective Study
Article Title	Shared decision-making improves adherence to mesalamine in ulcerative colitis: A prospective, multicenter, non-interventional cohort study in Germany
Manuscript Source	Unsolicited Manuscript
All Author List	Wolfgang Kruis, Petra Jessen, Julia Morgenstern, Birgitta Reimers, Nike Müller-Grage and Bernd Bokemeyer
Funding Agency and Grant Number
Corresponding Author	Wolfgang Kruis, Full Professor, MD, PhD, Department of Internal Medicine and Gastroenterology, Protestant Hospital Cologne-Kalk, Teaching Hospital of the University of Cologne, Buchforststr 2, Cologne 51103, Germany. wolfgang.kruis@googlemail.com
Key Words	Ulcerative colitis; Adherence; Shared decision-making; Mesalamine; Drug formulation; Granules
Core Tip	In this 12-month prospective study, we found that when patients were actively involved in choosing their mesalamine formulation, such as tablets versus granules, their adherence to therapy significantly improved. This was especially true when patients both preferred and received mesalamine granules. Importantly, patients who reported good adherence also experienced better outcomes, with significant improvements in disease activity over the course of the study. Our findings suggest that supporting shared decision-making in routine care and accommodating patient preferences, particularly regarding medication formulation, can make a difference in long-term management of ulcerative colitis.
Citation	<p>Kruis W, Jessen P, Morgenstern J, Reimers B, Müller-Grage N, Bokemeyer B. Shared decision-making improves adherence to mesalamine in ulcerative colitis: A prospective, multicenter, non-interventional cohort study in Germany. <i>World J Gastroenterol</i> 2025; 31(22): 101915</p>

Received	2024-10-09 09:50
Peer-Review Started	2024-10-09 09:50
To Make the First Decision
Return for Revision	2025-03-25 06:12
Revised	2025-04-25 11:20
Second Decision	2025-05-26 02:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-05-26 08:02
Articles in Press	2025-05-26 08:02
Publication Fee Transferred
Edit the Manuscript by Language Editor	2025-06-01 21:29
Typeset the Manuscript	2025-06-08 05:34

ISSN	1007-9327 (print) and 2219-2840 (online)
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